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Identification of a novel DGKα inhibitor for XLP-1 therapy by virtual screening.
Velnati S, Ruffo E, Massarotti A, Talmon M, Varma KSS, Gesu A, Fresu LG, Snow AL, Bertoni A, Capello D, Tron GC, Graziani A, Baldanzi G. Velnati S, et al. Among authors: massarotti a. Eur J Med Chem. 2019 Feb 15;164:378-390. doi: 10.1016/j.ejmech.2018.12.061. Epub 2018 Dec 26. Eur J Med Chem. 2019. PMID: 30611057 Free PMC article.
Structure activity relationship studies on Amb639752: toward the identification of a common pharmacophoric structure for DGKα inhibitors.
Velnati S, Massarotti A, Antona A, Talmon M, Fresu LG, Galetto AS, Capello D, Bertoni A, Mercalli V, Graziani A, Tron GC, Baldanzi G. Velnati S, et al. Among authors: massarotti a. J Enzyme Inhib Med Chem. 2020 Dec;35(1):96-108. doi: 10.1080/14756366.2019.1684911. J Enzyme Inhib Med Chem. 2020. PMID: 31690133 Free PMC article.
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.
Travelli C, Aprile S, Rahimian R, Grolla AA, Rogati F, Bertolotti M, Malagnino F, di Paola R, Impellizzeri D, Fusco R, Mercalli V, Massarotti A, Stortini G, Terrazzino S, Del Grosso E, Fakhfouri G, Troiani MP, Alisi MA, Grosa G, Sorba G, Canonico PL, Orsomando G, Cuzzocrea S, Genazzani AA, Galli U, Tron GC. Travelli C, et al. Among authors: massarotti a. J Med Chem. 2017 Mar 9;60(5):1768-1792. doi: 10.1021/acs.jmedchem.6b01392. Epub 2017 Feb 22. J Med Chem. 2017. PMID: 28165742
Bio-Inspired Dual-Selective BCL-2/c-MYC G-Quadruplex Binders: Design, Synthesis, and Anticancer Activity of Drug-like Imidazo[2,1-i]purine Derivatives.
Pelliccia S, Amato J, Capasso D, Di Gaetano S, Massarotti A, Piccolo M, Irace C, Tron GC, Pagano B, Randazzo A, Novellino E, Giustiniano M. Pelliccia S, et al. Among authors: massarotti a. J Med Chem. 2020 Mar 12;63(5):2035-2050. doi: 10.1021/acs.jmedchem.9b00262. Epub 2019 Jul 10. J Med Chem. 2020. PMID: 31241946
63 results