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Year Number of Results
2005 1
2006 1
2008 1
2009 1
2010 3
2012 4
2013 5
2014 5
2015 4
2016 5
2017 5
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2020 5
2021 8
2022 9
2023 4
2024 1

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65 results

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Page 1
Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
Krieger IV, Yalamanchili S, Dickson P, Engelhart CA, Zimmerman MD, Wood J, Clary E, Nguyen J, Thornton N, Centrella PA, Chan B, Cuozzo JW, Gengenbacher M, Guié MA, Guilinger JP, Bienstock C, Hartl H, Hupp CD, Jetson R, Satoh T, Yeoman JTS, Zhang Y, Dartois V, Schnappinger D, Keefe AD, Sacchettini JC. Krieger IV, et al. Among authors: gengenbacher m. ACS Infect Dis. 2024 Apr 5. doi: 10.1021/acsinfecdis.3c00592. Online ahead of print. ACS Infect Dis. 2024. PMID: 38577994
A preclinical model of TB meningitis to determine drug penetration and activity at the sites of disease.
Lanni F, Antilus Sainte R, Hansen M Jr, Parigi P, Kaya F, LoMauro K, Siow B, Wilkinson RJ, Wasserman S, Podell BK, Gengenbacher M, Dartois V. Lanni F, et al. Among authors: gengenbacher m. Antimicrob Agents Chemother. 2023 Dec 14;67(12):e0067123. doi: 10.1128/aac.00671-23. Epub 2023 Nov 15. Antimicrob Agents Chemother. 2023. PMID: 37966227 Free PMC article.
Wild mouse gut microbiota limits initial tuberculosis infection in BALB/c mice.
Xie M, Tsai CY, McAdams ZL, Oo M, Hansen M, Dougher M, Sansano A, Watson A, LoMauro K, Antilus-Sainte R, Ericsson A, Dartois V, Gengenbacher M. Xie M, et al. Among authors: gengenbacher m. PLoS One. 2023 Jul 26;18(7):e0288290. doi: 10.1371/journal.pone.0288290. eCollection 2023. PLoS One. 2023. PMID: 37494371 Free PMC article.
Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection.
Negatu DA, González Del Río R, Cacho-Izquierdo M, Barros-Aguirre D, Lelievre J, Rullas J, Casado P, Ganapathy US, Zimmerman MD, Gengenbacher M, Dartois V, Dick T. Negatu DA, et al. Among authors: gengenbacher m. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0145922. doi: 10.1128/aac.01459-22. Epub 2023 Jan 23. Antimicrob Agents Chemother. 2023. PMID: 36688684 Free PMC article.
Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance.
Lan T, Ganapathy US, Sharma S, Ahn YM, Zimmerman M, Molodtsov V, Hegde P, Gengenbacher M, Ebright RH, Dartois V, Freundlich JS, Dick T, Aldrich CC. Lan T, et al. Among authors: gengenbacher m. Angew Chem Int Ed Engl. 2022 Nov 7;61(45):e202211498. doi: 10.1002/anie.202211498. Epub 2022 Oct 12. Angew Chem Int Ed Engl. 2022. PMID: 36222275 Free PMC article.
Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus.
Madani A, Negatu DA, El Marrouni A, Miller RR, Boyce CW, Murgolo N, Bungard CJ, Zimmerman MD, Dartois V, Gengenbacher M, Olsen DB, Dick T. Madani A, et al. Among authors: gengenbacher m. Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0066922. doi: 10.1128/aac.00669-22. Epub 2022 Aug 25. Antimicrob Agents Chemother. 2022. PMID: 36005813 Free PMC article.
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.
Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA, Sullivan DF, Gengenbacher M, Dartois VA, Schnappinger D, Rock JM. Li S, et al. Among authors: gengenbacher m. Nat Microbiol. 2022 Jun;7(6):766-779. doi: 10.1038/s41564-022-01130-y. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637331 Free PMC article.
CinA mediates multidrug tolerance in Mycobacterium tuberculosis.
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M, Dartois V, Sacchettini JC, Rhee KY, Schnappinger D, Ehrt S. Kreutzfeldt KM, et al. Among authors: gengenbacher m. Nat Commun. 2022 Apr 22;13(1):2203. doi: 10.1038/s41467-022-29832-1. Nat Commun. 2022. PMID: 35459278 Free PMC article.
65 results