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Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling.
Atxabal U, Nycholat C, Pröpster JM, Fernández A, Oyenarte I, Lenza MP, Franconetti A, Soares CO, Coelho H, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J. Atxabal U, et al. Among authors: marcelo f. ACS Chem Biol. 2024 Feb 16;19(2):483-496. doi: 10.1021/acschembio.3c00664. Epub 2024 Feb 7. ACS Chem Biol. 2024. PMID: 38321945 Free PMC article.
Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins.
Lenza MP, Oyenarte I, Diercks T, Quintana JI, Gimeno A, Coelho H, Diniz A, Peccati F, Delgado S, Bosch A, Valle M, Millet O, Abrescia NGA, Palazón A, Marcelo F, Jiménez-Osés G, Jiménez-Barbero J, Ardá A, Ereño-Orbea J. Lenza MP, et al. Among authors: marcelo f. Angew Chem Int Ed Engl. 2020 Dec 21;59(52):23763-23771. doi: 10.1002/anie.202011015. Epub 2020 Oct 22. Angew Chem Int Ed Engl. 2020. PMID: 32915505 Free PMC article.
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, Delgado S, Núñez-Franco R, Garnica Marroquín CT, Coelho H, Unione L, Jiménez-Oses G, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J. Lenza MP, et al. Among authors: marcelo f. JACS Au. 2022 Dec 23;3(1):204-215. doi: 10.1021/jacsau.2c00592. eCollection 2023 Jan 23. JACS Au. 2022. PMID: 36711084 Free PMC article.
Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, Bosch A, Manisha P, Quintana JI, Oyenarte I, Unione L, Moure MJ, Azkargorta M, Atxabal U, Sobczak K, Elortza F, Sutherland JD, Barrio R, Marcelo F, Jiménez-Barbero J, Palazon A, Ereño-Orbea J. Lenza MP, et al. Among authors: marcelo f. Nat Commun. 2023 Jun 13;14(1):3496. doi: 10.1038/s41467-023-39119-8. Nat Commun. 2023. PMID: 37311743 Free PMC article.
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling.
Coelho H, Rivas ML, Grosso AS, Diniz A, Soares CO, Francisco RA, Dias JS, Compañon I, Sun L, Narimatsu Y, Vakhrushev SY, Clausen H, Cabrita EJ, Jiménez-Barbero J, Corzana F, Hurtado-Guerrero R, Marcelo F. Coelho H, et al. Among authors: marcelo f. JACS Au. 2022 Feb 24;2(3):631-645. doi: 10.1021/jacsau.1c00529. eCollection 2022 Mar 28. JACS Au. 2022. PMID: 35373202 Free PMC article.
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition.
Madariaga D, Martínez-Sáez N, Somovilla VJ, Coelho H, Valero-González J, Castro-López J, Asensio JL, Jiménez-Barbero J, Busto JH, Avenoza A, Marcelo F, Hurtado-Guerrero R, Corzana F, Peregrina JM. Madariaga D, et al. Among authors: marcelo f. ACS Chem Biol. 2015 Mar 20;10(3):747-56. doi: 10.1021/cb500855x. Epub 2014 Dec 10. ACS Chem Biol. 2015. PMID: 25457745
The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.
Coelho H, Matsushita T, Artigas G, Hinou H, Cañada FJ, Lo-Man R, Leclerc C, Cabrita EJ, Jiménez-Barbero J, Nishimura S, Garcia-Martín F, Marcelo F. Coelho H, et al. Among authors: marcelo f. J Am Chem Soc. 2015 Oct 7;137(39):12438-41. doi: 10.1021/jacs.5b06787. Epub 2015 Sep 22. J Am Chem Soc. 2015. PMID: 26366611
72 results