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[No title available]
[No authors listed] [No authors listed] PMID: 33453887
De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains.
Nawatha M, Rogers JM, Bonn SM, Livneh I, Lemma B, Mali SM, Vamisetti GB, Sun H, Bercovich B, Huang Y, Ciechanover A, Fushman D, Suga H, Brik A. Nawatha M, et al. Among authors: mali sm. Nat Chem. 2019 Jul;11(7):644-652. doi: 10.1038/s41557-019-0278-x. Epub 2019 Jun 10. Nat Chem. 2019. PMID: 31182821 Free PMC article.
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles.
Sun H, Mali SM, Singh SK, Meledin R, Brik A, Kwon YT, Kravtsova-Ivantsiv Y, Bercovich B, Ciechanover A. Sun H, et al. Among authors: mali sm. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):7805-7812. doi: 10.1073/pnas.1822148116. Epub 2019 Mar 13. Proc Natl Acad Sci U S A. 2019. PMID: 30867293 Free PMC article.
30 results