Maios C - Search Results

1

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.

Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C, Macklin-Isquierdo S, Perry S, Duhaime S, Maios C, Chang J, Perez J, Couto A, Lai J, Li Y, Alworth SV, Hendricks E, Wang Y, Zlokovic BV, Dickman DK, Parker JA, Zarnescu DC, Gao FB, Ichida JK. Hung ST, et al. Among authors: maios c. Cell. 2023 Feb 16;186(4):786-802.e28. doi: 10.1016/j.cell.2023.01.005. Epub 2023 Feb 7. Cell. 2023. PMID: 36754049 Free PMC article.

2

Genetic and pharmacological PARP inhibition reduces axonal degeneration in C. elegans models of ALS.

Tossing G, Livernoche R, Maios C, Bretonneau C, Labarre A, Parker JA. Tossing G, et al. Among authors: maios c. Hum Mol Genet. 2022 Sep 29;31(19):3313-3324. doi: 10.1093/hmg/ddac116. Hum Mol Genet. 2022. PMID: 35594544

3

A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans.

Labarre A, Tossing G, Maios C, Doyle JJ, Parker JA. Labarre A, et al. Among authors: maios c. MicroPubl Biol. 2021 Sep 22;2021:10.17912/micropub.biology.000473. doi: 10.17912/micropub.biology.000473. eCollection 2021. MicroPubl Biol. 2021. PMID: 34568776 Free PMC article.

4

Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.

Doyle JJ, Maios C, Vrancx C, Duhaime S, Chitramuthu B, Bennett HPJ, Bateman A, Parker JA. Doyle JJ, et al. Among authors: maios c. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2022115118. doi: 10.1073/pnas.2022115118. Proc Natl Acad Sci U S A. 2021. PMID: 34140407 Free PMC article.

5

Correction to: The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.

Bose P, Tremblay E, Maios C, Narasimhan V, Armstrong GAB, Liao M, Parker JA, Robitaille R, Wen XY, Barden C, Drapeau P. Bose P, et al. Among authors: maios c. Neurotherapeutics. 2021 Jul;18(3):2128. doi: 10.1007/s13311-021-01061-2. Neurotherapeutics. 2021. PMID: 34100189 Free PMC article. No abstract available.

6

Small Molecule Rescue of ATXN3 Toxicity in C. elegans via TFEB/HLH-30.

Fardghassemi Y, Maios C, Parker JA. Fardghassemi Y, et al. Among authors: maios c. Neurotherapeutics. 2021 Apr;18(2):1151-1165. doi: 10.1007/s13311-020-00993-5. Epub 2021 Mar 29. Neurotherapeutics. 2021. PMID: 33782863 Free PMC article.

7

Modulating the endoplasmic reticulum stress response attenuates neurodegeneration in a Caenorhabditiselegans model of spinal muscular atrophy.

Doyle JJ, Vrancx C, Maios C, Labarre A, Patten SA, Parker JA. Doyle JJ, et al. Among authors: maios c. Dis Model Mech. 2020 Dec 22;13(12):dmm041350. doi: 10.1242/dmm.041350. Dis Model Mech. 2020. PMID: 33106327 Free PMC article.

8

The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis.

Bose P, Tremblay E, Maios C, Narasimhan V, Armstrong GAB, Liao M, Parker JA, Robitaille R, Wen XY, Barden C, Drapeau P. Bose P, et al. Among authors: maios c. Neurotherapeutics. 2019 Oct;16(4):1149-1166. doi: 10.1007/s13311-019-00765-w. Neurotherapeutics. 2019. PMID: 31342410 Free PMC article.

9

RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement.

Abu-Baker A, Kharma N, Perreault J, Grant A, Shekarabi M, Maios C, Dona M, Neri C, Dion PA, Parker A, Varin L, Rouleau GA. Abu-Baker A, et al. Among authors: maios c. Mol Ther Nucleic Acids. 2019 Apr 15;15:12-25. doi: 10.1016/j.omtn.2019.02.003. Epub 2019 Feb 15. Mol Ther Nucleic Acids. 2019. PMID: 30831428 Free PMC article.

10

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, Kabashi E, Robitaille R, Korngut L, Parker JA, Drapeau P. Patten SA, et al. Among authors: maios c. JCI Insight. 2017 Nov 16;2(22):e97152. doi: 10.1172/jci.insight.97152. eCollection 2017 Nov 16. JCI Insight. 2017. PMID: 29202456 Free PMC article. Clinical Trial.

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