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Modeling human T1D-associated autoimmune processes.
Mol Metab. 2022 Feb;56:101417. doi: 10.1016/j.molmet.2021.101417. Epub 2021 Dec 10.
Mol Metab. 2022.
PMID: 34902607
Free PMC article.
Review.
T1D patient-derived hematopoietic stem cells are programmed to generate Tph, Tfh, and autoimmunity-associated B cell subsets in human immune system mice.
Vecchione A, Madley R, Danzl N, Borsotti C, Marharlooei MK, Li HW, Nauman G, Ding X, Ho SH, Fousteri G, Sykes M.
Vecchione A, et al. Among authors: madley r.
Clin Immunol. 2022 Jul;240:109048. doi: 10.1016/j.clim.2022.109048. Epub 2022 May 26.
Clin Immunol. 2022.
PMID: 35644520
Free PMC article.
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Negative selection of human T cells recognizing a naturally-expressed tissue-restricted antigen in the human thymus.
Madley R, Nauman G, Danzl N, Borsotti C, Khosravi Maharlooei M, Li HW, Chavez E, Creusot RJ, Nakayama M, Roep B, Sykes M.
Madley R, et al.
J Transl Autoimmun. 2020 Aug 9;3:100061. doi: 10.1016/j.jtauto.2020.100061. eCollection 2020.
J Transl Autoimmun. 2020.
PMID: 32875283
Free PMC article.
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Rapid thymectomy of NSG mice to analyze the role of native and grafted thymi in humanized mice.
Khosravi-Maharlooei M, Hoelzl M, Li HW, Madley RC, Waffarn EE, Danzl NM, Sykes M.
Khosravi-Maharlooei M, et al. Among authors: madley rc.
Eur J Immunol. 2020 Jan;50(1):138-141. doi: 10.1002/eji.201948205. Epub 2019 Nov 28.
Eur J Immunol. 2020.
PMID: 31583677
Free PMC article.
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Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs.
Nauman G, Danzl NM, Lee J, Borsotti C, Madley R, Fu J, Hölzl MA, Dahmani A, Dorronsoro Gonzalez A, Chavez É, Campbell SR, Yang S, Satwani P, Liu K, Sykes M.
Nauman G, et al. Among authors: madley r.
J Immunol. 2022 Apr 1;208(7):1652-1663. doi: 10.4049/jimmunol.2100966. Epub 2022 Mar 21.
J Immunol. 2022.
PMID: 35315788
Free PMC article.
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Role of Proinsulin Self-Association in Mutant INS Gene-Induced Diabetes of Youth.
Sun J, Xiong Y, Li X, Haataja L, Chen W, Mir SA, Lv L, Madley R, Larkin D, Anjum A, Dhayalan B, Rege N, Wickramasinghe NP, Weiss MA, Itkin-Ansari P, Kaufman RJ, Ostrov DA, Arvan P, Liu M.
Sun J, et al. Among authors: madley r.
Diabetes. 2020 May;69(5):954-964. doi: 10.2337/db19-1106. Epub 2020 Mar 5.
Diabetes. 2020.
PMID: 32139596
Free PMC article.
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Competitive Inhibition of the Endoplasmic Reticulum Signal Peptidase by Non-cleavable Mutant Preprotein Cargos.
Cui J, Chen W, Sun J, Guo H, Madley R, Xiong Y, Pan X, Wang H, Tai AW, Weiss MA, Arvan P, Liu M.
Cui J, et al. Among authors: madley r.
J Biol Chem. 2015 Nov 20;290(47):28131-28140. doi: 10.1074/jbc.M115.692350. Epub 2015 Oct 7.
J Biol Chem. 2015.
PMID: 26446786
Free PMC article.
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Positive charge in the n-region of the signal peptide contributes to efficient post-translational translocation of small secretory preproteins.
Guo H, Sun J, Li X, Xiong Y, Wang H, Shu H, Zhu R, Liu Q, Huang Y, Madley R, Wang Y, Cui J, Arvan P, Liu M.
Guo H, et al. Among authors: madley r.
J Biol Chem. 2018 Feb 9;293(6):1899-1907. doi: 10.1074/jbc.RA117.000922. Epub 2017 Dec 11.
J Biol Chem. 2018.
PMID: 29229776
Free PMC article.
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