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Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis.
Fang Z, Corbizi Fattori G, McKerrell T, Boucher RH, Jackson A, Fletcher RS, Forte D, Martin JE, Fox S, Roberts J, Glover R, Harris E, Bridges HR, Grassi L, Rodriguez-Meira A, Mead AJ, Knapper S, Ewing J, Butt NM, Jain M, Francis S, Clark FJ, Coppell J, McMullin MF, Wadelin F, Narayanan S, Milojkovic D, Drummond MW, Sekhar M, ElDaly H, Hirst J, Paramor M, Baxter EJ, Godfrey AL, Harrison CN, Méndez-Ferrer S. Fang Z, et al. Nat Commun. 2023 Nov 25;14(1):7725. doi: 10.1038/s41467-023-43175-5. Nat Commun. 2023. PMID: 38001082 Free PMC article. Clinical Trial.
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms.
Grockowiak E, Korn C, Rak J, Lysenko V, Hallou A, Panvini FM, Williams M, Fielding C, Fang Z, Khatib-Massalha E, García-García A, Li J, Khorshed RA, González-Antón S, Baxter EJ, Kusumbe A, Wilkins BS, Green A, Simons BD, Harrison CN, Green AR, Lo Celso C, Theocharides APA, Méndez-Ferrer S. Grockowiak E, et al. Nat Cancer. 2023 Aug;4(8):1193-1209. doi: 10.1038/s43018-023-00607-x. Epub 2023 Aug 7. Nat Cancer. 2023. PMID: 37550517 Free PMC article.
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells.
Viñado AC, Calvo IA, Cenzano I, Olaverri D, Cocera M, San Martin-Uriz P, Romero JP, Vilas-Zornoza A, Vera L, Gomez-Cebrian N, Puchades-Carrasco L, Lisi-Vega LE, Apaolaza I, Valera P, Guruceaga E, Granero-Molto F, Ripalda-Cemborain P, Luck TJ, Bullinger L, Planes FJ, Rifon JJ, Méndez-Ferrer S, Yusuf RZ, Pardo-Saganta A, Prosper F, Saez B. Viñado AC, et al. Leukemia. 2022 Aug;36(8):1969-1979. doi: 10.1038/s41375-022-01601-5. Epub 2022 May 26. Leukemia. 2022. PMID: 35618797 Free PMC article.
The EHA Research Roadmap: Hematopoietic Stem Cells and Allotransplantation.
Fibbe W, Bernardi R, Charbord P, Krause D, Lo Celso C, Méndez-Ferrer S, Mummery C, Oostendorp R, Raaijmakers M, Socié G, Staal F, Bacigalupo A. Fibbe W, et al. Hemasphere. 2022 Apr 29;6(5):e0714. doi: 10.1097/HS9.0000000000000714. eCollection 2022 May. Hemasphere. 2022. PMID: 35509429 Free PMC article. No abstract available.
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
Gadomski S, Fielding C, García-García A, Korn C, Kapeni C, Ashraf S, Villadiego J, Toro RD, Domingues O, Skepper JN, Michel T, Zimmer J, Sendtner R, Dillon S, Poole KES, Holdsworth G, Sendtner M, Toledo-Aral JJ, De Bari C, McCaskie AW, Robey PG, Méndez-Ferrer S. Gadomski S, et al. Cell Stem Cell. 2022 Apr 7;29(4):528-544.e9. doi: 10.1016/j.stem.2022.02.008. Epub 2022 Mar 10. Cell Stem Cell. 2022. PMID: 35276096 Free PMC article.
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