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Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis.
Zhang Y, Lazarus J, Steele NG, Yan W, Lee HJ, Nwosu ZC, Halbrook CJ, Menjivar RE, Kemp SB, Sirihorachai VR, Velez-Delgado A, Donahue K, Carpenter ES, Brown KL, Irizarry-Negron V, Nevison AC, Vinta A, Anderson MA, Crawford HC, Lyssiotis CA, Frankel TL, Bednar F, Pasca di Magliano M. Zhang Y, et al. Among authors: lyssiotis ca. Cancer Discov. 2020 Mar;10(3):422-439. doi: 10.1158/2159-8290.CD-19-0958. Epub 2020 Jan 7. Cancer Discov. 2020. PMID: 31911451 Free PMC article.
Adipocytes promote pancreatic cancer cell proliferation via glutamine transfer.
Meyer KA, Neeley CK, Baker NA, Washabaugh AR, Flesher CG, Nelson BS, Frankel TL, Lumeng CN, Lyssiotis CA, Wynn ML, Rhim AD, O'Rourke RW. Meyer KA, et al. Among authors: lyssiotis ca. Biochem Biophys Rep. 2016 Sep;7:144-149. doi: 10.1016/j.bbrep.2016.06.004. Epub 2016 Jun 7. Biochem Biophys Rep. 2016. PMID: 27617308 Free PMC article.
Metabolic Interactions in the Tumor Microenvironment.
Lyssiotis CA, Kimmelman AC. Lyssiotis CA, et al. Trends Cell Biol. 2017 Nov;27(11):863-875. doi: 10.1016/j.tcb.2017.06.003. Epub 2017 Jul 19. Trends Cell Biol. 2017. PMID: 28734735 Free PMC article. Review.
Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Cali Daylan AE, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M. Schofield HK, et al. Among authors: lyssiotis ca. JCI Insight. 2018 Jan 25;3(2):e97422. doi: 10.1172/jci.insight.97422. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367463 Free PMC article.
Menin regulates the serine biosynthetic pathway in Ewing sarcoma.
Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER. Svoboda LK, et al. Among authors: lyssiotis ca. J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28. J Pathol. 2018. PMID: 29672864 Free PMC article.
Fine-Tuning Mitochondrial Dysfunction and Reductive Carboxylation.
Halbrook CJ, Nwosu ZC, Lyssiotis CA. Halbrook CJ, et al. Among authors: lyssiotis ca. Trends Endocrinol Metab. 2018 Sep;29(9):599-602. doi: 10.1016/j.tem.2018.04.002. Epub 2018 Apr 23. Trends Endocrinol Metab. 2018. PMID: 29692332
Metabolism and epigenetics of pancreatic cancer stem cells.
Perusina Lanfranca M, Thompson JK, Bednar F, Halbrook C, Lyssiotis C, Levi B, Frankel TL. Perusina Lanfranca M, et al. Semin Cancer Biol. 2019 Aug;57:19-26. doi: 10.1016/j.semcancer.2018.09.008. Epub 2018 Sep 28. Semin Cancer Biol. 2019. PMID: 30273655 Free PMC article. Review.
196 results