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Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.
Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M, Schmidt F, Weisblum Y, Cioffi M, Li T, Rowdo FM, Martin ML, Guo CJ, Lyssiotis C, Layden BT, Dannenberg AJ, Bieniasz PD, Lee B, Inohara N, Matei I, Plemper RK, Zeng MY. Brown JA, et al. Among authors: lyssiotis c. Gut Microbes. 2022 Jan-Dec;14(1):2105609. doi: 10.1080/19490976.2022.2105609. Gut Microbes. 2022. PMID: 35915556 Free PMC article.
OXPHOS promotes apoptotic resistance and cellular persistence in TH17 cells in the periphery and tumor microenvironment.
Hong HS, Mbah NE, Shan M, Loesel K, Lin L, Sajjakulnukit P, Correa LO, Andren A, Lin J, Hayashi A, Magnuson B, Chen J, Li Z, Xie Y, Zhang L, Goldstein DR, Carty SA, Lei YL, Opipari AW, Argüello RJ, Kryczek I, Kamada N, Zou W, Franchi L, Lyssiotis CA. Hong HS, et al. Sci Immunol. 2022 Nov 25;7(77):eabm8182. doi: 10.1126/sciimmunol.abm8182. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399539 Free PMC article.
Unravelling specific diet and gut microbial contributions to inflammatory bowel disease.
Pereira GV, Boudaud M, Wolter M, Alexander C, De Sciscio A, Grant ET, Trindade BC, Pudlo NA, Singh S, Campbell A, Shan M, Zhang L, Willieme S, Kim K, Denike-Duval T, Bleich A, Schmidt TM, Kennedy L, Lyssiotis CA, Chen GY, Eaton KA, Desai MS, Martens EC. Pereira GV, et al. Among authors: lyssiotis ca. Res Sq [Preprint]. 2023 Mar 13:rs.3.rs-2518251. doi: 10.21203/rs.3.rs-2518251/v1. Res Sq. 2023. PMID: 36993463 Free PMC article. Preprint.
Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation.
Riwes MM, Golob JL, Magenau J, Shan M, Dick G, Braun T, Schmidt TM, Pawarode A, Anand S, Ghosh M, Maciejewski J, King D, Choi S, Yanik G, Geer M, Hillman E, Lyssiotis CA, Tewari M, Reddy P. Riwes MM, et al. Nat Med. 2023 Nov;29(11):2805-2813. doi: 10.1038/s41591-023-02587-y. Epub 2023 Oct 19. Nat Med. 2023. PMID: 37857710 Free PMC article. Clinical Trial.
Human Norovirus Triggers Primary B Cell Immune Activation In Vitro.
Mirabelli C, Jones MK, Young VL, Kolawole AO, Owusu I, Shan M, Abuaita B, Turula H, Trevino JG, Grigorova I, Lundy SK, Lyssiotis CA, Ward VK, Karst SM, Wobus CE. Mirabelli C, et al. Among authors: lyssiotis ca. mBio. 2022 Apr 26;13(2):e0017522. doi: 10.1128/mbio.00175-22. Epub 2022 Apr 11. mBio. 2022. PMID: 35404121 Free PMC article.
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, di Magliano MP, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. Kremer DM, et al. Among authors: lyssiotis ca. Nat Commun. 2021 Aug 11;12(1):4860. doi: 10.1038/s41467-021-24859-2. Nat Commun. 2021. PMID: 34381026 Free PMC article.
Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma.
Puca F, Yu F, Bartolacci C, Pettazzoni P, Carugo A, Huang-Hobbs E, Liu J, Zanca C, Carbone F, Del Poggetto E, Gumin J, Dasgupta P, Seth S, Srinivasan S, Lang FF, Sulman EP, Lorenzi PL, Tan L, Shan M, Tolstyka ZP, Kachman M, Zhang L, Gao S, Deem AK, Genovese G, Scaglioni PP, Lyssiotis CA, Viale A, Draetta GF. Puca F, et al. Among authors: lyssiotis ca. Cancer Discov. 2021 Nov;11(11):2904-2923. doi: 10.1158/2159-8290.CD-20-1437. Epub 2021 May 26. Cancer Discov. 2021. PMID: 34039636 Free PMC article.
H2S preconditioning induces long-lived perturbations in O2 metabolism.
Hanna DA, Diessl J, Guha A, Kumar R, Andren A, Lyssiotis C, Banerjee R. Hanna DA, et al. Among authors: lyssiotis c. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2319473121. doi: 10.1073/pnas.2319473121. Epub 2024 Mar 13. Proc Natl Acad Sci U S A. 2024. PMID: 38478695
197 results