Longo PA - Search Results

1

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.

Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD, Cole PA. Barnett BP, et al. Among authors: longo pa. Science. 2010 Dec 17;330(6011):1689-92. doi: 10.1126/science.1196154. Epub 2010 Nov 18. Science. 2010. PMID: 21097901 Free PMC article.

2

In vitro enzymatic characterization of near full length EGFR in activated and inhibited states.

Qiu C, Tarrant MK, Boronina T, Longo PA, Kavran JM, Cole RN, Cole PA, Leahy DJ. Qiu C, et al. Among authors: longo pa. Biochemistry. 2009 Jul 21;48(28):6624-32. doi: 10.1021/bi900755n. Biochemistry. 2009. PMID: 19518076 Free PMC article.

3

Mechanistic insights into the activation of oncogenic forms of EGF receptor.

Wang Z, Longo PA, Tarrant MK, Kim K, Head S, Leahy DJ, Cole PA. Wang Z, et al. Among authors: longo pa. Nat Struct Mol Biol. 2011 Nov 20;18(12):1388-93. doi: 10.1038/nsmb.2168. Nat Struct Mol Biol. 2011. PMID: 22101934 Free PMC article.

4

Transient mammalian cell transfection with polyethylenimine (PEI).

Longo PA, Kavran JM, Kim MS, Leahy DJ. Longo PA, et al. Methods Enzymol. 2013;529:227-40. doi: 10.1016/B978-0-12-418687-3.00018-5. Methods Enzymol. 2013. PMID: 24011049 Free PMC article.

5

Single cell cloning of a stable mammalian cell line.

Longo PA, Kavran JM, Kim MS, Leahy DJ. Longo PA, et al. Methods Enzymol. 2014;536:165-72. doi: 10.1016/B978-0-12-420070-8.00014-3. Methods Enzymol. 2014. PMID: 24423275

6

Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin.

Geisbrecht BV, Dowd KA, Barfield RW, Longo PA, Leahy DJ. Geisbrecht BV, et al. Among authors: longo pa. J Biol Chem. 2003 Aug 29;278(35):32561-8. doi: 10.1074/jbc.M302943200. Epub 2003 Jun 16. J Biol Chem. 2003. PMID: 12810718 Free article.

7

The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand.

Bouyain S, Longo PA, Li S, Ferguson KM, Leahy DJ. Bouyain S, et al. Among authors: longo pa. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15024-9. doi: 10.1073/pnas.0507591102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203964 Free PMC article.

8

A single ligand is sufficient to activate EGFR dimers.

Liu P, Cleveland TE 4th, Bouyain S, Byrne PO, Longo PA, Leahy DJ. Liu P, et al. Among authors: longo pa. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10861-6. doi: 10.1073/pnas.1201114109. Epub 2012 Jun 14. Proc Natl Acad Sci U S A. 2012. PMID: 22699492 Free PMC article.

9

A mammalian expression vector for expression and purification of secreted proteins for structural studies.

Leahy DJ, Dann CE 3rd, Longo P, Perman B, Ramyar KX. Leahy DJ, et al. Protein Expr Purif. 2000 Dec;20(3):500-6. doi: 10.1006/prep.2000.1331. Protein Expr Purif. 2000. PMID: 11087690 Free article.

10

Distinctive ganglioside patterns revealed by anti-ganglioside antibody binding to differentiating CG-4 oligodendrocytes.

Schnaar RL, Longo P, Yang LJ, Tai T. Schnaar RL, et al. Glycobiology. 1996 Apr;6(3):257-63. doi: 10.1093/glycob/6.3.257. Glycobiology. 1996. PMID: 8724133

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