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Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Costantino L, Ferrari S, Santucci M, Salo-Ahen OMH, Carosati E, Franchini S, Lauriola A, Pozzi C, Trande M, Gozzi G, Saxena P, Cannazza G, Losi L, Cardinale D, Venturelli A, Quotadamo A, Linciano P, Tagliazucchi L, Moschella MG, Guerrini R, Pacifico S, Luciani R, Genovese F, Henrich S, Alboni S, Santarem N, da Silva Cordeiro A, Giovannetti E, Peters GJ, Pinton P, Rimessi A, Cruciani G, Stroud RM, Wade RC, Mangani S, Marverti G, D'Arca D, Ponterini G, Costi MP. Costantino L, et al. Among authors: linciano p. Elife. 2022 Dec 7;11:e73862. doi: 10.7554/eLife.73862. Elife. 2022. PMID: 36475542 Free PMC article.
Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R).
Rossino G, Rui M, Pozzetti L, Schepmann D, Wünsch B, Zampieri D, Pellavio G, Laforenza U, Rinaldi S, Colombo G, Morelli L, Linciano P, Rossi D, Collina S. Rossino G, et al. Among authors: linciano p. Int J Mol Sci. 2020 Oct 18;21(20):7708. doi: 10.3390/ijms21207708. Int J Mol Sci. 2020. PMID: 33081037 Free PMC article.
69 results