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Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis.
Li XJ, Ong CK, Cao Y, Xiang YQ, Shao JY, Ooi A, Peng LX, Lu WH, Zhang Z, Petillo D, Qin L, Bao YN, Zheng FJ, Chia CS, Iyer NG, Kang TB, Zeng YX, Soo KC, Trent JM, Teh BT, Qian CN. Li XJ, et al. Cancer Res. 2011 Apr 15;71(8):3162-72. doi: 10.1158/0008-5472.CAN-10-3557. Epub 2011 Feb 2. Cancer Res. 2011. PMID: 21289131
Serglycin in human cancers.
Li XJ, Qian CN. Li XJ, et al. Chin J Cancer. 2011 Sep;30(9):585-9. doi: 10.5732/cjc.011.10314. Chin J Cancer. 2011. PMID: 21880179 Free PMC article. Review.
As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of AKT signaling.
Li XJ, Peng LX, Shao JY, Lu WH, Zhang JX, Chen S, Chen ZY, Xiang YQ, Bao YN, Zheng FJ, Zeng MS, Kang TB, Zeng YX, Teh BT, Qian CN. Li XJ, et al. Carcinogenesis. 2012 Jul;33(7):1302-9. doi: 10.1093/carcin/bgs181. Epub 2012 May 18. Carcinogenesis. 2012. PMID: 22610073 Free PMC article.
PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.
Jiang Y, Wang Y, Wang T, Hawke DH, Zheng Y, Li X, Zhou Q, Majumder S, Bi E, Liu DX, Huang S, Lu Z. Jiang Y, et al. Among authors: li x. Nat Commun. 2014 Nov 21;5:5566. doi: 10.1038/ncomms6566. Nat Commun. 2014. PMID: 25412762 Free PMC article.
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