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Tissue bioanalysis of biotherapeutics and drug targets to support PK/PD.
Neubert H, Fountain S, King L, Clark T, Weng Y, O'Hara DM, Li W, Leung S, Ray C, Palandra J, Ocaña MF, Chen J, Ji C, Wang M, Long K, Gorovits B, Fluhler E. Neubert H, et al. Among authors: li w. Bioanalysis. 2012 Nov;4(21):2589-604. doi: 10.4155/bio.12.234. Bioanalysis. 2012. PMID: 23173794 Review.
Monitoring cellular accumulation of 3'-deoxy-3'-fluorothymidine (FLT) and its monophosphate metabolite (FLT-MP) by LC-MS/MS as a measure of cell proliferation in vitro.
Li W, Araya M, Elliott M, Kang X, Gerk PM, Halquist MS, Karnes HT, Zhang C, O'Brien PJ. Li W, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 15;879(28):2963-70. doi: 10.1016/j.jchromb.2011.08.024. Epub 2011 Aug 31. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21925976
Development and validation of an LC-MS/MS method for quantification of cyclic guanosine 3',5'-monophosphate (cGMP) in clinical applications: a comparison with a EIA method.
Zhang Y, Dufield D, Klover J, Li W, Szekely-Klepser G, Lepsy C, Sadagopan N. Zhang Y, et al. Among authors: li w. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Feb 15;877(5-6):513-20. doi: 10.1016/j.jchromb.2008.12.063. Epub 2009 Jan 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2009. PMID: 19179124
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