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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery.
Xia Y, Xie Y, Yu Z, Xiao H, Jiang G, Zhou X, Yang Y, Li X, Zhao M, Li L, Zheng M, Han S, Zong Z, Meng X, Deng H, Ye H, Fa Y, Wu H, Oldfield E, Hu X, Liu W, Shi Y, Zhang Y. Xia Y, et al. Among authors: li x, li l. Cell. 2018 Nov 1;175(4):1059-1073.e21. doi: 10.1016/j.cell.2018.08.070. Epub 2018 Sep 27. Cell. 2018. PMID: 30270039 Free article.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Among authors: li l. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.
The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement.
Chen CC, Hu X, Tang X, Yang Y, Ko TP, Gao J, Zheng Y, Huang JW, Yu Z, Li L, Han S, Cai N, Zhang Y, Liu W, Guo RT. Chen CC, et al. Among authors: li l. Angew Chem Int Ed Engl. 2018 Nov 12;57(46):15060-15064. doi: 10.1002/anie.201808231. Epub 2018 Oct 23. Angew Chem Int Ed Engl. 2018. PMID: 30222239
A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated Vγ9Vδ2 T Cell Activation.
Yang Y, Li L, Yuan L, Zhou X, Duan J, Xiao H, Cai N, Han S, Ma X, Liu W, Chen CC, Wang L, Li X, Chen J, Kang N, Chen J, Shen Z, Malwal SR, Liu W, Shi Y, Oldfield E, Guo RT, Zhang Y. Yang Y, et al. Among authors: li x, li l. Immunity. 2019 Apr 16;50(4):1043-1053.e5. doi: 10.1016/j.immuni.2019.02.016. Epub 2019 Mar 19. Immunity. 2019. PMID: 30902636 Free article.
Farnesyl pyrophosphate is a new danger signal inducing acute cell death.
Chen J, Zhang X, Li L, Ma X, Yang C, Liu Z, Li C, Fernandez-Cabezudo MJ, Al-Ramadi BK, Wu C, Huang W, Zhang Y, Zhang Y, Liu W. Chen J, et al. Among authors: li c, li l. PLoS Biol. 2021 Apr 26;19(4):e3001134. doi: 10.1371/journal.pbio.3001134. eCollection 2021 Apr. PLoS Biol. 2021. PMID: 33901180 Free PMC article.
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