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Antiproliferative and quinone reductase-inducing activities of withanolides derivatives.
García ME, Nicotra VE, Oberti JC, Ríos-Luci C, León LG, Marler L, Li G, Pezzuto JM, van Breemen RB, Padrón JM, Hueso-Falcón I, Estévez-Braun A. García ME, et al. Among authors: li g. Eur J Med Chem. 2014 Jul 23;82:68-81. doi: 10.1016/j.ejmech.2014.05.045. Epub 2014 May 20. Eur J Med Chem. 2014. PMID: 24878636
Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
Smith BR, Santos MB, Marshall MS, Cantuti-Castelvetri L, Lopez-Rosas A, Li G, van Breemen R, Claycomb KI, Gallea JI, Celej MS, Crocker SJ, Givogri MI, Bongarzone ER. Smith BR, et al. Among authors: li g. J Pathol. 2014 Apr;232(5):509-21. doi: 10.1002/path.4328. Epub 2014 Feb 20. J Pathol. 2014. PMID: 24415155 Free PMC article.
The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.
Yu LF, Brek Eaton J, Zhang HK, Sabath E, Hanania T, Li GN, van Breemen RB, Whiteaker P, Liu Q, Wu J, Chang YC, Lukas RJ, Brunner D, Kozikowski AP. Yu LF, et al. Pharmacol Res Perspect. 2014 Apr;2(2):e00026. doi: 10.1002/prp2.26. Epub 2014 Mar 12. Pharmacol Res Perspect. 2014. PMID: 25505580 Free PMC article.
Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells.
Pituch KC, Moyano AL, Lopez-Rosas A, Marottoli FM, Li G, Hu C, van Breemen R, Månsson JE, Givogri MI. Pituch KC, et al. Among authors: li g. J Biol Chem. 2015 Mar 13;290(11):7040-53. doi: 10.1074/jbc.M115.636498. Epub 2015 Jan 20. J Biol Chem. 2015. PMID: 25605750 Free PMC article.
Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A.
Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolić D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Hajirahimkhan A, et al. Among authors: li g. Chem Res Toxicol. 2015 Nov 16;28(11):2130-41. doi: 10.1021/acs.chemrestox.5b00310. Epub 2015 Nov 5. Chem Res Toxicol. 2015. PMID: 26473469 Free PMC article.
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