Lesser CF - Search Results

1

Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.

Lynch JP, González-Prieto C, Reeves AZ, Bae S, Powale U, Godbole NP, Tremblay JM, Schmidt FI, Ploegh HL, Kansra V, Glickman JN, Leong JM, Shoemaker CB, Garrett WS, Lesser CF. Lynch JP, et al. Among authors: lesser cf. Cell Host Microbe. 2023 Apr 12;31(4):634-649.e8. doi: 10.1016/j.chom.2023.03.007. Epub 2023 Mar 31. Cell Host Microbe. 2023. PMID: 37003258 Free PMC article.

2

PROT₃EcT, engineered Escherichia coli for the targeted delivery of therapeutics.

González-Prieto C, Lynch JP, Lesser CF. González-Prieto C, et al. Among authors: lesser cf. Trends Mol Med. 2023 Nov;29(11):968-969. doi: 10.1016/j.molmed.2023.07.007. Epub 2023 Aug 11. Trends Mol Med. 2023. PMID: 37574350 No abstract available.

3

A hierarchy of cell death pathways confers layered resistance to shigellosis in mice.

Roncaioli JL, Babirye JP, Chavez RA, Liu FL, Turcotte EA, Lee AY, Lesser CF, Vance RE. Roncaioli JL, et al. Among authors: lesser cf. Elife. 2023 Jan 16;12:e83639. doi: 10.7554/eLife.83639. Elife. 2023. PMID: 36645406 Free PMC article.

4

Case Report and Clinical Reasoning: Fulminant Liver Failure and Invasive Aspergillosis Following Ocrelizumab Treatment in a 21 Year-Old Woman.

McEntire CRS, Lesser CF, Venna N. McEntire CRS, et al. Among authors: lesser cf. Neurohospitalist. 2023 Jan;13(1):96-102. doi: 10.1177/19418744221130385. Epub 2022 Oct 10. Neurohospitalist. 2023. PMID: 36531849 Free PMC article.

5

LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro.

Dickinson MS, Kutsch M, Sistemich L, Hernandez D, Piro AS, Needham D, Lesser CF, Herrmann C, Coers J. Dickinson MS, et al. Among authors: lesser cf. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2216028120. doi: 10.1073/pnas.2216028120. Epub 2023 Apr 6. Proc Natl Acad Sci U S A. 2023. PMID: 37023136 Free PMC article.

6

Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation.

Goers L, Kim K, Stedman TC, Canning PJ, Mou X, Ernst NH, Coers J, Lesser CF. Goers L, et al. Among authors: lesser cf. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2218469120. doi: 10.1073/pnas.2218469120. Epub 2023 Apr 4. Proc Natl Acad Sci U S A. 2023. PMID: 37014865 Free PMC article.

7

The Shigella Spp. Type III Effector Protein OspB Is a Cysteine Protease.

Wood TE, Westervelt KA, Yoon JM, Eshleman HD, Levy R, Burnes H, Slade DJ, Lesser CF, Goldberg MB. Wood TE, et al. Among authors: lesser cf. mBio. 2022 Jun 28;13(3):e0127022. doi: 10.1128/mbio.01270-22. Epub 2022 May 31. mBio. 2022. PMID: 35638611 Free PMC article.

8

A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling.

Alphonse N, Wanford JJ, Voak AA, Gay J, Venkhaya S, Burroughs O, Mathew S, Lee T, Evans SL, Zhao W, Frowde K, Alrehaili A, Dickenson RE, Munk M, Panina S, Mahmood IF, Llorian M, Stanifer ML, Boulant S, Berchtold MW, Bergeron JRC, Wack A, Lesser CF, Odendall C. Alphonse N, et al. Among authors: lesser cf. Cell. 2022 Jun 23;185(13):2354-2369.e17. doi: 10.1016/j.cell.2022.04.028. Epub 2022 May 13. Cell. 2022. PMID: 35568036 Free PMC article.

9

Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics.

Lynch JP, Goers L, Lesser CF. Lynch JP, et al. Among authors: lesser cf. Trends Pharmacol Sci. 2022 Sep;43(9):772-786. doi: 10.1016/j.tips.2022.02.002. Epub 2022 Feb 26. Trends Pharmacol Sci. 2022. PMID: 35232591 Free PMC article. Review.

10

The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.

Kutsch M, González-Prieto C, Lesser CF, Coers J. Kutsch M, et al. Among authors: lesser cf. Pathog Dis. 2021 Apr 24;79(5):ftab023. doi: 10.1093/femspd/ftab023. Pathog Dis. 2021. PMID: 33885766 Free PMC article.

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