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Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing.
Seegren PV, Downs TK, Stremska ME, Harper LR, Cao R, Olson RJ, Upchurch CM, Doyle CA, Kennedy J, Stipes EL, Leitinger N, Periasamy A, Desai BN. Seegren PV, et al. Among authors: leitinger n. Cell Rep. 2020 Nov 24;33(8):108411. doi: 10.1016/j.celrep.2020.108411. Cell Rep. 2020. PMID: 33238121 Free PMC article.
Pannexin 1 Channels as an Unexpected New Target of the Anti-Hypertensive Drug Spironolactone.
Good ME, Chiu YH, Poon IKH, Medina CB, Butcher JT, Mendu SK, DeLalio LJ, Lohman AW, Leitinger N, Barrett E, Lorenz UM, Desai BN, Jaffe IZ, Bayliss DA, Isakson BE, Ravichandran KS. Good ME, et al. Among authors: leitinger n. Circ Res. 2018 Feb 16;122(4):606-615. doi: 10.1161/CIRCRESAHA.117.312380. Epub 2017 Dec 13. Circ Res. 2018. PMID: 29237722 Free PMC article.
Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.
Schappe MS, Szteyn K, Stremska ME, Mendu SK, Downs TK, Seegren PV, Mahoney MA, Dixit S, Krupa JK, Stipes EJ, Rogers JS, Adamson SE, Leitinger N, Desai BN. Schappe MS, et al. Among authors: leitinger n. Immunity. 2018 Jan 16;48(1):59-74.e5. doi: 10.1016/j.immuni.2017.11.026. Immunity. 2018. PMID: 29343440 Free PMC article.
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2.
Kreutzberger AJB, Kiessling V, Doyle CA, Schenk N, Upchurch CM, Elmer-Dixon M, Ward AE, Preobraschenski J, Hussein SS, Tomaka W, Seelheim P, Kattan I, Harris M, Liang B, Kenworthy AK, Desai BN, Leitinger N, Anantharam A, Castle JD, Tamm LK. Kreutzberger AJB, et al. Among authors: leitinger n. Elife. 2020 Nov 9;9:e62506. doi: 10.7554/eLife.62506. Elife. 2020. PMID: 33164744 Free PMC article.
Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels.
Senthivinayagam S, Serbulea V, Upchurch CM, Polanowska-Grabowska R, Mendu SK, Sahu S, Jayaguru P, Aylor KW, Chordia MD, Steinberg L, Oberholtzer N, Uchiyama S, Inada N, Lorenz UM, Harris TE, Keller SR, Meher AK, Kadl A, Desai BN, Kundu BK, Leitinger N. Senthivinayagam S, et al. Among authors: leitinger n. Mol Metab. 2021 Feb;44:101130. doi: 10.1016/j.molmet.2020.101130. Epub 2020 Nov 25. Mol Metab. 2021. PMID: 33248294 Free PMC article.
128 results