Leil TA - Search Results

1

A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins.

Kierzek AM, Hickling TP, Figueroa I, Kalvass JC, Nijsen M, Mohan K, Veldman GM, Yamada A, Sayama H, Yokoo S, Gulati A, Dhanikula RS, Gokemeijer J, Leil TA, Thalhauser CJ, Giorgi M, Swat MJ, Chelliah V, Small BG, Benson N, Walker M, Gadkar K, Quarmby V, Deng R, Ferrante A, Dickinson GL, Van Der Walt JS, Zhou L, Chen X, Jones HM, Narula J, Tourdot S, Lavé T, Ribba B, van der Graaf PH. Kierzek AM, et al. Among authors: leil ta. CPT Pharmacometrics Syst Pharmacol. 2019 Nov;8(11):773-776. doi: 10.1002/psp4.12465. Epub 2019 Oct 8. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31529677 Free PMC article. No abstract available.

2

Evaluating a Multiscale Mechanistic Model of the Immune System to Predict Human Immunogenicity for a Biotherapeutic in Phase 1.

Hamuro L, Tirucherai GS, Crawford SM, Nayeem A, Pillutla RC, DeSilva BS, Leil TA, Thalhauser CJ. Hamuro L, et al. Among authors: leil ta. AAPS J. 2019 Jul 24;21(5):94. doi: 10.1208/s12248-019-0361-7. AAPS J. 2019. PMID: 31342199 Clinical Trial.

3

QSP Toolbox: Computational Implementation of Integrated Workflow Components for Deploying Multi-Scale Mechanistic Models.

Cheng Y, Thalhauser CJ, Smithline S, Pagidala J, Miladinov M, Vezina HE, Gupta M, Leil TA, Schmidt BJ. Cheng Y, et al. Among authors: leil ta. AAPS J. 2017 Jul;19(4):1002-1016. doi: 10.1208/s12248-017-0100-x. Epub 2017 May 24. AAPS J. 2017. PMID: 28540623

4

Antibodies to Modulate Surface Receptor Systems Are Often Bivalent and Must Compete in a Two-Dimensional Cell Contact Region.

Schmidt BJ, Bee C, Han M, Jing Y, Cheng Y, Tenney DJ, Leil TA. Schmidt BJ, et al. Among authors: leil ta. CPT Pharmacometrics Syst Pharmacol. 2019 Dec;8(12):873-877. doi: 10.1002/psp4.12468. Epub 2019 Oct 23. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31529681 Free PMC article. No abstract available.

5

Population Pharmacokinetics of Apixaban in Subjects With Nonvalvular Atrial Fibrillation.

Cirincione B, Kowalski K, Nielsen J, Roy A, Thanneer N, Byon W, Boyd R, Wang X, Leil T, LaCreta F, Ueno T, Oishi M, Frost C. Cirincione B, et al. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):728-738. doi: 10.1002/psp4.12347. Epub 2018 Sep 30. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30259707 Free PMC article.

6

Virtual Populations for Quantitative Systems Pharmacology Models.

Cheng Y, Straube R, Alnaif AE, Huang L, Leil TA, Schmidt BJ. Cheng Y, et al. Among authors: leil ta. Methods Mol Biol. 2022;2486:129-179. doi: 10.1007/978-1-0716-2265-0_8. Methods Mol Biol. 2022. PMID: 35437722

7

Investigating Transporter-Mediated Drug-Drug Interactions Using a Physiologically Based Pharmacokinetic Model of Rosuvastatin.

Wang Q, Zheng M, Leil T. Wang Q, et al. CPT Pharmacometrics Syst Pharmacol. 2017 Apr;6(4):228-238. doi: 10.1002/psp4.12168. Epub 2017 Mar 13. CPT Pharmacometrics Syst Pharmacol. 2017. PMID: 28296193 Free PMC article.

8

A bayesian perspective on estimation of variability and uncertainty in mechanism-based models.

Leil TA. Leil TA. CPT Pharmacometrics Syst Pharmacol. 2014 Jun 25;3(6):e121. doi: 10.1038/psp.2014.19. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 24964283 Free PMC article.

9

Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism-Based Pharmacometric Model.

Leil TA, Kasichayanula S, Boulton DW, LaCreta F. Leil TA, et al. CPT Pharmacometrics Syst Pharmacol. 2014 Jun 25;3(6):e120. doi: 10.1038/psp.2014.18. CPT Pharmacometrics Syst Pharmacol. 2014. PMID: 24964282 Free PMC article.

10

Editorial: The emerging discipline of quantitative systems pharmacology.

Leil TA, Ermakov S. Leil TA, et al. Front Pharmacol. 2015 Jun 30;6:129. doi: 10.3389/fphar.2015.00129. eCollection 2015. Front Pharmacol. 2015. PMID: 26175687 Free PMC article. No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

32 results

Search Page