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Metagenomics-enabled reverse-genetics assembly and characterization of myotis bat morbillivirus.
Ikegame S, Carmichael JC, Wells H, Furler O'Brien RL, Acklin JA, Chiu HP, Oguntuyo KY, Cox RM, Patel AR, Kowdle S, Stevens CS, Eckley M, Zhan S, Lim JK, Veit EC, Evans MJ, Hashiguchi T, Durigon E, Schountz T, Epstein JH, Plemper RK, Daszak P, Anthony SJ, Lee B. Ikegame S, et al. Among authors: lee b. Nat Microbiol. 2023 Jun;8(6):1108-1122. doi: 10.1038/s41564-023-01380-4. Epub 2023 May 4. Nat Microbiol. 2023. PMID: 37142773
Evidence for henipavirus spillover into human populations in Africa.
Pernet O, Schneider BS, Beaty SM, LeBreton M, Yun TE, Park A, Zachariah TT, Bowden TA, Hitchens P, Ramirez CM, Daszak P, Mazet J, Freiberg AN, Wolfe ND, Lee B. Pernet O, et al. Among authors: lee b. Nat Commun. 2014 Nov 18;5:5342. doi: 10.1038/ncomms6342. Nat Commun. 2014. PMID: 25405640 Free PMC article.
A structural basis for antibody-mediated neutralization of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex.
Avanzato VA, Oguntuyo KY, Escalera-Zamudio M, Gutierrez B, Golden M, Kosakovsky Pond SL, Pryce R, Walter TS, Seow J, Doores KJ, Pybus OG, Munster VJ, Lee B, Bowden TA. Avanzato VA, et al. Among authors: lee b. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25057-25067. doi: 10.1073/pnas.1912503116. Epub 2019 Nov 25. Proc Natl Acad Sci U S A. 2019. PMID: 31767754 Free PMC article.
Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
Cox RM, Sourimant J, Toots M, Yoon JJ, Ikegame S, Govindarajan M, Watkinson RE, Thibault P, Makhsous N, Lin MJ, Marengo JR, Sticher Z, Kolykhalov AA, Natchus MG, Greninger AL, Lee B, Plemper RK. Cox RM, et al. Among authors: lee b. Nat Microbiol. 2020 Oct;5(10):1232-1246. doi: 10.1038/s41564-020-0752-7. Epub 2020 Jul 13. Nat Microbiol. 2020. PMID: 32661315 Free PMC article.
Alpha-1-antitrypsin and its variant-dependent role in COVID-19 pathogenesis.
Stevens CS, Oguntuyo KY, Kowdle S, Brambilla L, Haas G, Gowlikar A, Siddiquey MN, Schilke RM, Woolard MD, Zhang H, Acklin JA, Ikegame S, Huang CT, Lim JK, Cross RW, Geisbert TW, Ivanov SS, Kamil JP; Alpha-1 Foundation; Lee B. Stevens CS, et al. Among authors: lee b. bioRxiv [Preprint]. 2023 May 8:2020.08.14.248880. doi: 10.1101/2020.08.14.248880. bioRxiv. 2023. PMID: 32817940 Free PMC article. Preprint.
Quantifying absolute neutralization titers against SARS-CoV-2 by a standardized virus neutralization assay allows for cross-cohort comparisons of COVID-19 sera.
Oguntuyo KY, Stevens CS, Hung CT, Ikegame S, Acklin JA, Kowdle SS, Carmichael JC, Chiu HP, Azarm KD, Haas GD, Amanat F, Klingler J, Baine I, Arinsburg S, Bandres JC, Siddiquey MNA, Schilke RM, Woolard MD, Zhang H; COVIDAR Argentina Consortium; Duty AJ, Kraus TA, Moran TM, Tortorella D, Lim JK, Gamarnik AV, Hioe CE, Zolla-Pazner S, Ivanov SS, Kamil JP, Krammer F, Lee B. Oguntuyo KY, et al. Among authors: lee b. medRxiv [Preprint]. 2020 Aug 27:2020.08.13.20157222. doi: 10.1101/2020.08.13.20157222. medRxiv. 2020. PMID: 32817961 Free PMC article. Updated. Preprint.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Among authors: lee b. Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028. Epub 2020 Oct 20. Cell. 2021. PMID: 33147444 Free PMC article.
Role of IgM and IgA Antibodies in the Neutralization of SARS-CoV-2.
Klingler J, Weiss S, Itri V, Liu X, Oguntuyo KY, Stevens C, Ikegame S, Hung CT, Enyindah-Asonye G, Amanat F, Baine I, Arinsburg S, Bandres JC, Kojic EM, Stoever J, Jurczyszak D, Bermudez-Gonzalez M, Nádas A, Liu S, Lee B, Zolla-Pazner S, Hioe CE. Klingler J, et al. Among authors: lee b. medRxiv [Preprint]. 2020 Dec 21:2020.08.18.20177303. doi: 10.1101/2020.08.18.20177303. medRxiv. 2020. PMID: 33173891 Free PMC article. Updated. Preprint.
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