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Inflammasome activation and IL-1 signaling during placental malaria induce poor pregnancy outcomes.
Reis AS, Barboza R, Murillo O, Barateiro A, Peixoto EPM, Lima FA, Gomes VM, Dombrowski JG, Leal VNC, Araujo F, Bandeira CL, Araujo RBD, Neres R, Souza RM, Costa FTM, Pontillo A, Bevilacqua E, Wrenger C, Wunderlich G, Palmisano G, Labriola L, Bortoluci KR, Penha-Gonçalves C, Gonçalves LA, Epiphanio S, Marinho CRF. Reis AS, et al. Among authors: leal vnc. Sci Adv. 2020 Mar 4;6(10):eaax6346. doi: 10.1126/sciadv.aax6346. eCollection 2020 Mar. Sci Adv. 2020. PMID: 32181339 Free PMC article.
Inflammasome genetics and complex diseases: a comprehensive review.
Fernandes FP, Leal VNC, Souza de Lima D, Reis EC, Pontillo A. Fernandes FP, et al. Among authors: leal vnc. Eur J Hum Genet. 2020 Oct;28(10):1307-1321. doi: 10.1038/s41431-020-0631-y. Epub 2020 Jun 4. Eur J Hum Genet. 2020. PMID: 32499599 Free PMC article. Review.
Combining Host Genetics and Functional Analysis to Depict Inflammasome Contribution in Tuberculosis Susceptibility and Outcome in Endemic Areas.
Souza De Lima D, Bomfim CCB, Leal VNC, Reis EC, Soares JLS, Fernandes FP, Amaral EP, Loures FV, Ogusku MM, Lima MRD, Sadahiro A, Pontillo A. Souza De Lima D, et al. Among authors: leal vnc. Front Immunol. 2020 Oct 21;11:550624. doi: 10.3389/fimmu.2020.550624. eCollection 2020. Front Immunol. 2020. PMID: 33193317 Free PMC article.
A common variant close to the "tripwire" linker region of NLRP1 contributes to severe COVID-19.
Leal VNC, Paulino LM, Cambui RAG, Zupelli TG, Yamada SM, Oliveira LAT, Dutra VF, Bub CB, Sakashita AM, Yokoyama APH, Kutner JM, Vieira CA, Santiago WMS, Andrade MMS, Teixeira FME, Alberca RW, Gozzi-Silva SC, Yendo TM, Netto LC, Duarte AJS, Sato MN, Venturini J, Pontillo A. Leal VNC, et al. Inflamm Res. 2023 Nov;72(10-11):1933-1940. doi: 10.1007/s00011-022-01670-3. Epub 2022 Nov 23. Inflamm Res. 2023. PMID: 36416944 Free PMC article.
Resveratrol Downmodulates Neutrophil Extracellular Trap (NET) Generation by Neutrophils in Patients with Severe COVID-19.
de Souza Andrade MM, Leal VNC, Fernandes IG, Gozzi-Silva SC, Beserra DR, Oliveira EA, Teixeira FME, Yendo TM, Sousa MDGT, Teodoro WR, Oliveira LM, Alberca RW, Aoki V, Duarte AJS, Sato MN. de Souza Andrade MM, et al. Among authors: leal vnc. Antioxidants (Basel). 2022 Aug 29;11(9):1690. doi: 10.3390/antiox11091690. Antioxidants (Basel). 2022. PMID: 36139764 Free PMC article.
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