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Stability study of unmodified siRNA and relevance to clinical use.
Hickerson RP, Vlassov AV, Wang Q, Leake D, Ilves H, Gonzalez-Gonzalez E, Contag CH, Johnston BH, Kaspar RL. Hickerson RP, et al. Among authors: leake d. Oligonucleotides. 2008 Dec;18(4):345-54. doi: 10.1089/oli.2008.0149. Oligonucleotides. 2008. PMID: 18844576 Free PMC article.
Single-nucleotide-specific siRNA targeting in a dominant-negative skin model.
Hickerson RP, Smith FJ, Reeves RE, Contag CH, Leake D, Leachman SA, Milstone LM, McLean WH, Kaspar RL. Hickerson RP, et al. Among authors: leake d. J Invest Dermatol. 2008 Mar;128(3):594-605. doi: 10.1038/sj.jid.5701060. Epub 2007 Oct 11. J Invest Dermatol. 2008. PMID: 17914454 Free article.
Development of quantitative molecular clinical end points for siRNA clinical trials.
Hickerson RP, Leachman SA, Pho LN, Gonzalez-Gonzalez E, Smith FJ, McLean WH, Contag CH, Leake D, Milstone LM, Kaspar RL. Hickerson RP, et al. Among authors: leake d. J Invest Dermatol. 2011 May;131(5):1029-36. doi: 10.1038/jid.2010.372. Epub 2010 Dec 30. J Invest Dermatol. 2011. PMID: 21191405 Free article.
244 results