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Drug resistance mechanisms and novel drug targets for tuberculosis therapy.
Islam MM, Hameed HMA, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. Islam MM, et al. Among authors: lamichhane g. J Genet Genomics. 2017 Jan 20;44(1):21-37. doi: 10.1016/j.jgg.2016.10.002. Epub 2016 Oct 11. J Genet Genomics. 2017. PMID: 28117224 Review.
Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.
Ochsner UA, De Groote MA, Jarvis TC, Liu H, Youmans T, Hoang T, Ribble W, Day J, Li W, Pearce C, Walz A, Panthi CM, Rimal B, Stevens CM, Zgurskaya HI, Jackson M, Ordway D, Gonzalez-Juarrero M, Sun X, Lamichhane G, Mason C. Ochsner UA, et al. Among authors: lamichhane g. Tuberculosis (Edinb). 2023 Jan;138:102288. doi: 10.1016/j.tube.2022.102288. Epub 2022 Nov 29. Tuberculosis (Edinb). 2023. PMID: 36470124 Free PMC article.
Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice.
Jain SK, Hernandez-Abanto SM, Cheng QJ, Singh P, Ly LH, Klinkenberg LG, Morrison NE, Converse PJ, Nuermberger E, Grosset J, McMurray DN, Karakousis PC, Lamichhane G, Bishai WR. Jain SK, et al. Among authors: lamichhane g. J Infect Dis. 2007 Jun 1;195(11):1634-42. doi: 10.1086/517526. Epub 2007 Apr 23. J Infect Dis. 2007. PMID: 17471433
Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.
Converse PJ, Karakousis PC, Klinkenberg LG, Kesavan AK, Ly LH, Allen SS, Grosset JH, Jain SK, Lamichhane G, Manabe YC, McMurray DN, Nuermberger EL, Bishai WR. Converse PJ, et al. Among authors: lamichhane g. Infect Immun. 2009 Mar;77(3):1230-7. doi: 10.1128/IAI.01117-08. Epub 2008 Dec 22. Infect Immun. 2009. PMID: 19103767 Free PMC article.
The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models.
Converse PJ, Eisenach KD, Theus SA, Nuermberger EL, Tyagi S, Ly LH, Geiman DE, Guo H, Nolan ST, Akar NC, Klinkenberg LG, Gupta R, Lun S, Karakousis PC, Lamichhane G, McMurray DN, Grosset JH, Bishai WR. Converse PJ, et al. Among authors: lamichhane g. PLoS One. 2010 Apr 21;5(4):e10289. doi: 10.1371/journal.pone.0010289. PLoS One. 2010. PMID: 20422019 Free PMC article.
Structural and functional features of enzymes of Mycobacterium tuberculosis peptidoglycan biosynthesis as targets for drug development.
Moraes GL, Gomes GC, Monteiro de Sousa PR, Alves CN, Govender T, Kruger HG, Maguire GE, Lamichhane G, Lameira J. Moraes GL, et al. Among authors: lamichhane g. Tuberculosis (Edinb). 2015 Mar;95(2):95-111. doi: 10.1016/j.tube.2015.01.006. Epub 2015 Jan 29. Tuberculosis (Edinb). 2015. PMID: 25701501 Free PMC article. Review.
110 results