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Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion.
Sun X, Wu B, Chiang HC, Deng H, Zhang X, Xiong W, Liu J, Rozeboom AM, Harris BT, Blommaert E, Gomez A, Garcia RE, Zhou Y, Mitra P, Prevost M, Zhang D, Banik D, Isaacs C, Berry D, Lai C, Chaldekas K, Latham PS, Brantner CA, Popratiloff A, Jin VX, Zhang N, Hu Y, Pujana MA, Curiel TJ, An Z, Li R. Sun X, et al. Among authors: lai c. Nature. 2021 Nov;599(7886):673-678. doi: 10.1038/s41586-021-04057-2. Epub 2021 Nov 3. Nature. 2021. PMID: 34732895 Free PMC article.
TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML.
Vadakekolathu J, Lai C, Reeder S, Church SE, Hood T, Lourdusamy A, Rettig MP, Aldoss I, Advani AS, Godwin J, Wieduwilt MJ, Arellano M, Muth J, Yau TO, Ravandi F, Sweet K, Altmann H, Foulds GA, Stölzel F, Middeke JM, Ciciarello M, Curti A, Valk PJM, Löwenberg B, Gojo I, Bornhäuser M, DiPersio JF, Davidson-Moncada JK, Rutella S. Vadakekolathu J, et al. Among authors: lai c. Blood Adv. 2020 Oct 27;4(20):5011-5024. doi: 10.1182/bloodadvances.2020002512. Blood Adv. 2020. PMID: 33057635 Free PMC article.
Real-world effectiveness of intensive chemotherapy with 7&3 versus venetoclax and hypomethylating agent in acute myeloid leukemia.
Matthews AH, Perl AE, Luger SM, Gill SI, Lai C, Porter DL, Skuli S, Bruno XJ, Carroll MP, Freyer CW, Carulli A, Babushok DV, Frey NV, Hexner EO, Martin ME, McCurdy SR, Stadtmauer EA, Loren AW, Paralkar VR, Maillard IP, Pratz KW. Matthews AH, et al. Among authors: lai c. Am J Hematol. 2023 Aug;98(8):1254-1264. doi: 10.1002/ajh.26991. Epub 2023 Jun 19. Am J Hematol. 2023. PMID: 37334852 Free PMC article.
TP53 in AML and MDS: The new (old) kid on the block.
Marks JA, Wang X, Fenu EM, Bagg A, Lai C. Marks JA, et al. Among authors: lai c. Blood Rev. 2023 Jul;60:101055. doi: 10.1016/j.blre.2023.101055. Epub 2023 Feb 14. Blood Rev. 2023. PMID: 36841672 Review.
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