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The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11.
Lafage-Pochitaloff M, Gerby B, Baccini V, Largeaud L, Fregona V, Prade N, Juvin PY, Jamrog L, Bories P, Hébrard S, Lagarde S, Mansat-De Mas V, Dovey OM, Yusa K, Vassiliou GS, Jansen JH, Tekath T, Rombaut D, Ameye G, Barin C, Bidet A, Boudjarane J, Collonge-Rame MA, Gervais C, Ittel A, Lefebvre C, Luquet I, Michaux L, Nadal N, Poirel HA, Radford-Weiss I, Ribourtout B, Richebourg S, Struski S, Terré C, Tigaud I, Penther D, Eclache V, Fontenay M, Broccardo C, Delabesse E. Lafage-Pochitaloff M, et al. Among authors: lagarde s. Blood Adv. 2022 Jan 25;6(2):386-398. doi: 10.1182/bloodadvances.2021005311. Blood Adv. 2022. PMID: 34638130 Free PMC article.
Impact of TP53 mutations in acute myeloid leukemia patients treated with azacitidine.
Bories P, Prade N, Lagarde S, Cabarrou B, Largeaud L, Plenecassagnes J, Luquet I, De Mas V, Filleron T, Cassou M, Sarry A, Fornecker LM, Simand C, Bertoli S, Recher C, Delabesse E. Bories P, et al. Among authors: lagarde s. PLoS One. 2020 Oct 1;15(10):e0238795. doi: 10.1371/journal.pone.0238795. eCollection 2020. PLoS One. 2020. PMID: 33001991 Free PMC article.
NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.
Struski S, Lagarde S, Bories P, Puiseux C, Prade N, Cuccuini W, Pages MP, Bidet A, Gervais C, Lafage-Pochitaloff M, Roche-Lestienne C, Barin C, Penther D, Nadal N, Radford-Weiss I, Collonge-Rame MA, Gaillard B, Mugneret F, Lefebvre C, Bart-Delabesse E, Petit A, Leverger G, Broccardo C, Luquet I, Pasquet M, Delabesse E. Struski S, et al. Among authors: lagarde s. Leukemia. 2017 Mar;31(3):565-572. doi: 10.1038/leu.2016.267. Epub 2016 Oct 3. Leukemia. 2017. PMID: 27694926
PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.
Jamrog L, Chemin G, Fregona V, Coster L, Pasquet M, Oudinet C, Rouquié N, Prade N, Lagarde S, Cresson C, Hébrard S, Nguyen Huu NS, Bousquet M, Quelen C, Brousset P, Mancini SJC, Delabesse E, Khamlichi AA, Gerby B, Broccardo C. Jamrog L, et al. Among authors: lagarde s. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10357-10362. doi: 10.1073/pnas.1721678115. Epub 2018 Sep 26. Proc Natl Acad Sci U S A. 2018. PMID: 30257940 Free PMC article.
PAX5A and PAX5B isoforms are both efficient to drive B cell differentiation.
Cresson C, Péron S, Jamrog L, Rouquié N, Prade N, Dubois M, Hébrard S, Lagarde S, Gerby B, Mancini SJC, Cogné M, Delabesse E, Delpy L, Broccardo C. Cresson C, et al. Among authors: lagarde s. Oncotarget. 2018 Aug 28;9(67):32841-32854. doi: 10.18632/oncotarget.26003. eCollection 2018 Aug 28. Oncotarget. 2018. PMID: 30214688 Free PMC article.
Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia.
Laurent AP, Siret A, Ignacimouttou C, Panchal K, Diop M, Jenni S, Tsai YC, Roos-Weil D, Aid Z, Prade N, Lagarde S, Plassard D, Pierron G, Daudigeos E, Lecluse Y, Droin N, Bornhauser BC, Cheung LC, Crispino JD, Gaudry M, Bernard OA, Macintyre E, Barin Bonnigal C, Kotecha RS, Geoerger B, Ballerini P, Bourquin JP, Delabesse E, Mercher T, Malinge S. Laurent AP, et al. Among authors: lagarde s. Clin Cancer Res. 2020 Jul 1;26(13):3307-3318. doi: 10.1158/1078-0432.CCR-19-3519. Epub 2020 Mar 27. Clin Cancer Res. 2020. PMID: 32220889 Free PMC article.
Spectrum of Kidney Disorders Associated with T-Cell Immunoclones.
Piedrafita A, Vergez F, Belliere J, Prades N, Colombat M, Huart A, Rieu JB, Lagarde S, Del Bello A, Kamar N, Chauveau D, Laurent C, Oberic L, Ysebaert L, Ribes D, Faguer S. Piedrafita A, et al. Among authors: lagarde s. J Clin Med. 2022 Jan 25;11(3):604. doi: 10.3390/jcm11030604. J Clin Med. 2022. PMID: 35160055 Free PMC article.
332 results