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Cardiac tissue model of immune-induced dysfunction reveals the role of free mitochondrial DNA and the therapeutic effects of exosomes.
Lu RXZ, Rafatian N, Zhao Y, Wagner KT, Beroncal EL, Li B, Lee C, Chen J, Churcher E, Vosoughi D, Liu C, Wang Y, Baker A, Trahtemberg U, Li B, Pierro A, Andreazza AC, Dos Santos CC, Radisic M. Lu RXZ, et al. Sci Adv. 2024 Mar 29;10(13):eadk0164. doi: 10.1126/sciadv.adk0164. Epub 2024 Mar 27. Sci Adv. 2024. PMID: 38536913 Free PMC article.
Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation.
Wauchop M, Rafatian N, Zhao Y, Chen W, Gagliardi M, Massé S, Cox BJ, Lai P, Liang T, Landau S, Protze S, Gao XD, Wang EY, Tung KC, Laksman Z, Lu RXZ, Keller G, Nanthakumar K, Radisic M, Backx PH. Wauchop M, et al. Among authors: lu rxz. Biomaterials. 2023 Oct;301:122255. doi: 10.1016/j.biomaterials.2023.122255. Epub 2023 Jul 26. Biomaterials. 2023. PMID: 37651922
Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the role of free mitochondrial DNA and therapeutic effects of endothelial exosomes.
Lu RXZ, Rafatian N, Zhao Y, Wagner KT, Beroncal EL, Li B, Lee C, Chen J, Churcher E, Vosoughi D, Wang Y, Baker A, Trahtemberg U, Li B, Pierro A, Andreazza AC, Dos Santos CC, Radisic M. Lu RXZ, et al. bioRxiv [Preprint]. 2023 Aug 9:2023.08.09.552495. doi: 10.1101/2023.08.09.552495. bioRxiv. 2023. PMID: 37609237 Free PMC article. Updated. Preprint.
37 results