López-Cara LC - Search Results

1

Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors.

Schiaffino-Ortega S, Mariotto E, Luque-Navarro PM, Kimatrai-Salvador M, Rios-Marco P, Hurtado-Guerrero R, Marco C, Carrasco-Jimenez MP, Viola G, López-Cara LC. Schiaffino-Ortega S, et al. Among authors: lopez cara lc. Pharmaceutics. 2021 Aug 29;13(9):1360. doi: 10.3390/pharmaceutics13091360. Pharmaceutics. 2021. PMID: 34575436 Free PMC article.

2

New non-symmetrical choline kinase inhibitors.

Schiaffino-Ortega S, López-Cara LC, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Espinosa A, Marco C, Entrena A. Schiaffino-Ortega S, et al. Bioorg Med Chem. 2013 Nov 15;21(22):7146-54. doi: 10.1016/j.bmc.2013.09.003. Epub 2013 Sep 11. Bioorg Med Chem. 2013. PMID: 24080101

3

1H, 13C NMR studies of new 3-aminophenol isomers linked to pyridinium salts.

Schiaffino-Ortega S, Espinosa A, Gallo MA, López-Cara LC, Entrena A. Schiaffino-Ortega S, et al. Magn Reson Chem. 2014 Jan-Feb;52(1-2):40-6. doi: 10.1002/mrc.4025. Epub 2013 Oct 30. Magn Reson Chem. 2014. PMID: 24170481

4

Choline kinase active site provides features for designing versatile inhibitors.

Serran-Aguilera L, Nuti R, López-Cara LC, Ríos-Marco P, Carrasco MP, Marco C, Entrena A, Macchiarulo A, Hurtado-Guerrero R. Serran-Aguilera L, et al. Curr Top Med Chem. 2014;14(23):2684-93. doi: 10.2174/1568026614666141216093337. Curr Top Med Chem. 2014. PMID: 25515750

5

New more polar symmetrical bipyridinic compounds: new strategy for the inhibition of choline kinase α1.

Castro-Navas FF, Schiaffino-Ortega S, Carrasco-Jimenez MP, Ríos-Marco P, Marco C, Espinosa A, Gallo MA, Mariotto E, Basso G, Viola G, Entrena-Guadix A, López-Cara LC. Castro-Navas FF, et al. Future Med Chem. 2015;7(4):417-36. doi: 10.4155/fmc.15.1. Future Med Chem. 2015. PMID: 25875870

6

Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).

Schiaffino-Ortega S, Baglioni E, Mariotto E, Bortolozzi R, Serrán-Aguilera L, Ríos-Marco P, Carrasco-Jimenez MP, Gallo MA, Hurtado-Guerrero R, Marco C, Basso G, Viola G, Entrena A, López-Cara LC. Schiaffino-Ortega S, et al. Sci Rep. 2016 Mar 31;6:23793. doi: 10.1038/srep23793. Sci Rep. 2016. PMID: 27029499 Free PMC article.

7

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Tabrizi MA, Lopez-Cara LC, Ferla S, Brancale A, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Basso G, Viola G. Romagnoli R, et al. Sci Rep. 2016 May 24;6:26602. doi: 10.1038/srep26602. Sci Rep. 2016. PMID: 27216165 Free PMC article.

8

¹ H and ¹³ C NMR spectral assignments of 1,1'-(((ethane-1,2-diylbis(oxy))bis(4,1-phenylene))bis(methylene))-bispyridinium and -bisquinolinium bromide derivatives.

Schiaffino-Ortega S, Kimatrai-Salvador M, Baglioni E, Gallo MA, Entrena Guadix A, Lopez-Cara LC. Schiaffino-Ortega S, et al. Magn Reson Chem. 2016 Nov;54(11):905-911. doi: 10.1002/mrc.4468. Epub 2016 Jul 11. Magn Reson Chem. 2016. PMID: 27402422 No abstract available.

9

Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1.

Serrán-Aguilera L, Nuti R, López-Cara LC, Mezo MÁ, Macchiarulo A, Entrena A, Hurtado-Guerrero R. Serrán-Aguilera L, et al. Mol Inform. 2015 Jun;34(6-7):458-66. doi: 10.1002/minf.201400140. Epub 2015 Jun 18. Mol Inform. 2015. PMID: 27490389

10

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Salvador MK, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Porcù E, Basso G, Viola G. Romagnoli R, et al. Sci Rep. 2017 Apr 13;7:46356. doi: 10.1038/srep46356. Sci Rep. 2017. PMID: 28406191 Free PMC article.

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