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HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J. Neubert P, et al. Among authors: kurts c. Autophagy. 2019 Nov;15(11):1899-1916. doi: 10.1080/15548627.2019.1596483. Epub 2019 Apr 14. Autophagy. 2019. PMID: 30982460 Free PMC article.
Lack of PPARγ in myeloid cells confers resistance to Listeria monocytogenes infection.
Abdullah Z, Geiger S, Nino-Castro A, Böttcher JP, Muraliv E, Gaidt M, Schildberg FA, Riethausen K, Flossdorf J, Krebs W, Chakraborty T, Kurts C, Schultze JL, Knolle PA, Klotz L. Abdullah Z, et al. Among authors: kurts c. PLoS One. 2012;7(5):e37349. doi: 10.1371/journal.pone.0037349. Epub 2012 May 21. PLoS One. 2012. PMID: 22629382 Free PMC article.
A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation.
Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C. Jobin K, et al. Among authors: kurts c. Sci Transl Med. 2020 Mar 25;12(536):eaay3850. doi: 10.1126/scitranslmed.aay3850. Sci Transl Med. 2020. PMID: 32213629
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. Neubert P, et al. Among authors: kurts c. PLoS Biol. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32569301 Free PMC article.
Sodium and its manifold impact on our immune system.
Jobin K, Müller DN, Jantsch J, Kurts C. Jobin K, et al. Among authors: kurts c. Trends Immunol. 2021 Jun;42(6):469-479. doi: 10.1016/j.it.2021.04.002. Epub 2021 May 4. Trends Immunol. 2021. PMID: 33962888 Free article. Review.
237 results