More trouble with FGF23: a novel role in systemic immunosuppression

Zeinab Abdullah; Christian Kurts

doi:10.1016/j.kint.2016.04.002

More trouble with FGF23: a novel role in systemic immunosuppression

Kidney Int. 2016 Jun;89(6):1176-7. doi: 10.1016/j.kint.2016.04.002.

Authors

Zeinab Abdullah¹, Christian Kurts²

Affiliations

¹ Institute of Experimental Immunology, University of Bonn, Bonn, Germany.
² Institute of Experimental Immunology, University of Bonn, Bonn, Germany. Electronic address: ckurts@uni-bonn.de.

PMID: 27181769
DOI: 10.1016/j.kint.2016.04.002

Abstract

A recent study describes impaired neutrophil function as another adverse effect of the excessive levels of FGF23 found in the circulation of patients with chronic kidney disease. These findings shed light on the mechanisms by which chronic kidney disease leads to systemic immunosuppression.

Publication types

Comment

MeSH terms

Fibroblast Growth Factor-23
Fibroblast Growth Factors*
Humans
Renal Insufficiency, Chronic*

Substances

FGF23 protein, human
Fibroblast Growth Factors
Fibroblast Growth Factor-23