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22 results

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Page 1
A chemoproteomic portrait of the oncometabolite fumarate.
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.
Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.
Zengeya TT, Garlick JM, Kulkarni RA, Miley M, Roberts AM, Yang Y, Crooks DR, Sourbier C, Linehan WM, Meier JL. Zengeya TT, et al. Among authors: kulkarni ra. J Am Chem Soc. 2016 Dec 14;138(49):15813-15816. doi: 10.1021/jacs.6b09706. Epub 2016 Nov 30. J Am Chem Soc. 2016. PMID: 27960310 Free PMC article.
Photoinducible Oncometabolite Detection.
Kulkarni RA, Briney CA, Crooks DR, Bergholtz SE, Mushti C, Lockett SJ, Lane AN, Fan TW, Swenson RE, Marston Linehan W, Meier JL. Kulkarni RA, et al. Chembiochem. 2019 Feb 1;20(3):360-365. doi: 10.1002/cbic.201800651. Epub 2018 Dec 13. Chembiochem. 2019. PMID: 30358041 Free PMC article.
Epigenetic regulation by endogenous metabolite pharmacology.
Kulkarni RA, Montgomery DC, Meier JL. Kulkarni RA, et al. Curr Opin Chem Biol. 2019 Aug;51:30-39. doi: 10.1016/j.cbpa.2019.02.002. Epub 2019 Mar 15. Curr Opin Chem Biol. 2019. PMID: 30884380 Free PMC article. Review.
Chemical cryptology of cancer's histone code.
Kulkarni RA, Meier JL. Kulkarni RA, et al. Chem Biol. 2014 Nov 20;21(11):1419-21. doi: 10.1016/j.chembiol.2014.11.003. Epub 2014 Nov 20. Chem Biol. 2014. PMID: 25457120 Free PMC article.
Global Profiling of Acetyltransferase Feedback Regulation.
Montgomery DC, Garlick JM, Kulkarni RA, Kennedy S, Allali-Hassani A, Kuo YM, Andrews AJ, Wu H, Vedadi M, Meier JL. Montgomery DC, et al. Among authors: kulkarni ra. J Am Chem Soc. 2016 May 25;138(20):6388-91. doi: 10.1021/jacs.6b03036. Epub 2016 May 17. J Am Chem Soc. 2016. PMID: 27149119 Free PMC article.
Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.
Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, Weissman AM, Linehan WM, Blair IA, Snyder NW, Meier JL. Kulkarni RA, et al. Cell Chem Biol. 2017 Feb 16;24(2):231-242. doi: 10.1016/j.chembiol.2017.01.002. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163016 Free PMC article.
Bioorthogonal pro-metabolites for profiling short chain fatty acylation.
Sinclair WR, Shrimp JH, Zengeya TT, Kulkarni RA, Garlick JM, Luecke H, Worth AJ, Blair IA, Snyder NW, Meier JL. Sinclair WR, et al. Among authors: kulkarni ra. Chem Sci. 2017 Dec 8;9(5):1236-1241. doi: 10.1039/c7sc00247e. eCollection 2018 Feb 7. Chem Sci. 2017. PMID: 29675169 Free PMC article.
Modular synthesis of cell-permeating 2-ketoglutarate esters.
Zengeya TT, Kulkarni RA, Meier JL. Zengeya TT, et al. Among authors: kulkarni ra. Org Lett. 2015 May 15;17(10):2326-9. doi: 10.1021/acs.orglett.5b00737. Epub 2015 Apr 27. Org Lett. 2015. PMID: 25915096 Free PMC article.
Statin therapy inhibits fatty acid synthase via dynamic protein modifications.
Trub AG, Wagner GR, Anderson KA, Crown SB, Zhang GF, Thompson JW, Ilkayeva OR, Stevens RD, Grimsrud PA, Kulkarni RA, Backos DS, Meier JL, Hirschey MD. Trub AG, et al. Among authors: kulkarni ra. Nat Commun. 2022 May 10;13(1):2542. doi: 10.1038/s41467-022-30060-w. Nat Commun. 2022. PMID: 35538051 Free PMC article.
22 results