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Cell Adhesion by Integrins.
Bachmann M, Kukkurainen S, Hytönen VP, Wehrle-Haller B. Bachmann M, et al. Among authors: kukkurainen s. Physiol Rev. 2019 Oct 1;99(4):1655-1699. doi: 10.1152/physrev.00036.2018. Physiol Rev. 2019. PMID: 31313981 Free article. Review.
The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering.
Kukkurainen S, Azizi L, Zhang P, Jacquier MC, Baikoghli M, von Essen M, Tuukkanen A, Laitaoja M, Liu X, Rahikainen R, Orłowski A, Jänis J, Määttä JAE, Varjosalo M, Vattulainen I, Róg T, Svergun D, Cheng RH, Wu J, Hytönen VP, Wehrle-Haller B. Kukkurainen S, et al. J Cell Sci. 2020 Oct 12;133(19):jcs239202. doi: 10.1242/jcs.239202. J Cell Sci. 2020. PMID: 33046605 Free PMC article.
Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Zhang P, Azizi L, Kukkurainen S, Gao T, Baikoghli M, Jacquier MC, Sun Y, Määttä JAE, Cheng RH, Wehrle-Haller B, Hytönen VP, Wu J. Zhang P, et al. Among authors: kukkurainen s. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32402-32412. doi: 10.1073/pnas.2014583117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288722 Free PMC article.
The talin-integrin interface under mechanical stress.
Kukkurainen S, Määttä JA, Saeger J, Valjakka J, Vogel V, Hytönen VP. Kukkurainen S, et al. Mol Biosyst. 2014 Dec;10(12):3217-28. doi: 10.1039/c4mb00341a. Mol Biosyst. 2014. PMID: 25277990
PIP2 and Talin Join Forces to Activate Integrin.
Orłowski A, Kukkurainen S, Pöyry A, Rissanen S, Vattulainen I, Hytönen VP, Róg T. Orłowski A, et al. Among authors: kukkurainen s. J Phys Chem B. 2015 Sep 24;119(38):12381-9. doi: 10.1021/acs.jpcb.5b06457. Epub 2015 Sep 9. J Phys Chem B. 2015. PMID: 26309152
19 results