Kuhn RJ - Search Results

1

A Prototype-Pathogen Approach for the Development of Flavivirus Countermeasures.

Kuhn RJ, Barrett ADT, Desilva AM, Harris E, Kramer LD, Montgomery RR, Pierson TC, Sette A, Diamond MS. Kuhn RJ, et al. J Infect Dis. 2023 Oct 18;228(Suppl 6):S398-S413. doi: 10.1093/infdis/jiad193. J Infect Dis. 2023. PMID: 37849402 Review.

2

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody.

Kaufmann B, Nybakken GE, Chipman PR, Zhang W, Diamond MS, Fremont DH, Kuhn RJ, Rossmann MG. Kaufmann B, et al. Among authors: kuhn rj. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12400-4. doi: 10.1073/pnas.0603488103. Epub 2006 Aug 8. Proc Natl Acad Sci U S A. 2006. PMID: 16895988 Free PMC article.

3

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.

Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Lok SM, et al. Among authors: kuhn rj. Nat Struct Mol Biol. 2008 Mar;15(3):312-7. doi: 10.1038/nsmb.1382. Epub 2008 Feb 10. Nat Struct Mol Biol. 2008. PMID: 18264114

4

Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development.

Pierson TC, Fremont DH, Kuhn RJ, Diamond MS. Pierson TC, et al. Among authors: kuhn rj. Cell Host Microbe. 2008 Sep 11;4(3):229-38. doi: 10.1016/j.chom.2008.08.004. Cell Host Microbe. 2008. PMID: 18779049 Free PMC article. Review.

5

Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody.

Cherrier MV, Kaufmann B, Nybakken GE, Lok SM, Warren JT, Chen BR, Nelson CA, Kostyuchenko VA, Holdaway HA, Chipman PR, Kuhn RJ, Diamond MS, Rossmann MG, Fremont DH. Cherrier MV, et al. Among authors: kuhn rj. EMBO J. 2009 Oct 21;28(20):3269-76. doi: 10.1038/emboj.2009.245. Epub 2009 Aug 27. EMBO J. 2009. PMID: 19713934 Free PMC article.

6

Capturing a flavivirus pre-fusion intermediate.

Kaufmann B, Chipman PR, Holdaway HA, Johnson S, Fremont DH, Kuhn RJ, Diamond MS, Rossmann MG. Kaufmann B, et al. Among authors: kuhn rj. PLoS Pathog. 2009 Nov;5(11):e1000672. doi: 10.1371/journal.ppat.1000672. Epub 2009 Nov 26. PLoS Pathog. 2009. PMID: 19956725 Free PMC article.

7

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354.

Kaufmann B, Vogt MR, Goudsmit J, Holdaway HA, Aksyuk AA, Chipman PR, Kuhn RJ, Diamond MS, Rossmann MG. Kaufmann B, et al. Among authors: kuhn rj. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18950-5. doi: 10.1073/pnas.1011036107. Epub 2010 Oct 18. Proc Natl Acad Sci U S A. 2010. PMID: 20956322 Free PMC article.

8

Capturing a virus while it catches its breath.

Pierson TC, Kuhn RJ. Pierson TC, et al. Among authors: kuhn rj. Structure. 2012 Feb 8;20(2):200-2. doi: 10.1016/j.str.2012.01.014. Structure. 2012. PMID: 22325768 Free PMC article.

9

Dengue structure differs at the temperatures of its human and mosquito hosts.

Zhang X, Sheng J, Plevka P, Kuhn RJ, Diamond MS, Rossmann MG. Zhang X, et al. Among authors: kuhn rj. Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):6795-9. doi: 10.1073/pnas.1304300110. Epub 2013 Apr 8. Proc Natl Acad Sci U S A. 2013. PMID: 23569243 Free PMC article.

10

Combined effects of the structural heterogeneity and dynamics of flaviviruses on antibody recognition.

Dowd KA, Mukherjee S, Kuhn RJ, Pierson TC. Dowd KA, et al. Among authors: kuhn rj. J Virol. 2014 Oct;88(20):11726-37. doi: 10.1128/JVI.01140-14. Epub 2014 Jul 30. J Virol. 2014. PMID: 25078693 Free PMC article.

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