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Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Kalogriopoulos NA, Rees SD, Ngo T, Kopcho NJ, Ilatovskiy AV, Sun N, Komives EA, Chang G, Ghosh P, Kufareva I. Kalogriopoulos NA, et al. Among authors: kufareva i. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16394-16403. doi: 10.1073/pnas.1906658116. Epub 2019 Jul 30. Proc Natl Acad Sci U S A. 2019. PMID: 31363053 Free PMC article.
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin.
Swanson L, Katkar GD, Tam J, Pranadinata RF, Chareddy Y, Coates J, Anandachar MS, Castillo V, Olson J, Nizet V, Kufareva I, Das S, Ghosh P. Swanson L, et al. Among authors: kufareva i. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26895-26906. doi: 10.1073/pnas.2011667117. Epub 2020 Oct 14. Proc Natl Acad Sci U S A. 2020. PMID: 33055214 Free PMC article.
Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi.
Kalogriopoulos NA, Lopez-Sanchez I, Lin C, Ngo T, Midde KK, Roy S, Aznar N, Murray F, Garcia-Marcos M, Kufareva I, Ghassemian M, Ghosh P. Kalogriopoulos NA, et al. Among authors: kufareva i. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28763-28774. doi: 10.1073/pnas.2004699117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139573 Free PMC article.
94 results