Kuduk SD - Search Results

1

Mild Intramolecular Ring Opening of Oxetanes.

DeRatt LG, Lawson EC, Wang CY, Kuduk SD. DeRatt LG, et al. Among authors: kuduk sd. Org Lett. 2019 Dec 6;21(23):9642-9645. doi: 10.1021/acs.orglett.9b03810. Epub 2019 Nov 19. Org Lett. 2019. PMID: 31742420

2

Tandem Amination/Oxetane Ring Opening toward Benzomorpholines.

DeRatt LG, Wang CY, Kuduk SD. DeRatt LG, et al. Among authors: kuduk sd. J Org Chem. 2021 Dec 3;86(23):17482-17486. doi: 10.1021/acs.joc.1c02166. Epub 2021 Nov 22. J Org Chem. 2021. PMID: 34807596

3

Tandem Suzuki Coupling/Intramolecular Oxetane Ring Opening to Form Polycyclic Ring Systems.

DeRatt LG, Lawson EC, Kumar K, Hwang SS, DesJarlais RL, Kuduk SD. DeRatt LG, et al. Among authors: kuduk sd. Org Lett. 2020 Aug 7;22(15):5828-5832. doi: 10.1021/acs.orglett.0c01899. Epub 2020 Jul 23. Org Lett. 2020. PMID: 32702238

4

Synthesis of 4-Alkylated Isocoumarins via Pd-Catalyzed α-Arylation Reaction.

Plunkett S, DeRatt LG, Kuduk SD, Balsells J. Plunkett S, et al. Among authors: kuduk sd. Org Lett. 2020 Oct 2;22(19):7662-7666. doi: 10.1021/acs.orglett.0c02851. Epub 2020 Sep 24. Org Lett. 2020. PMID: 32969657

5

A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.

DeRatt LG, Christine Pietsch E, Tanner A, Shaffer P, Jacoby E, Wang W, Kazmi F, Zhang X, Attar RM, Edwards JP, Kuduk SD. DeRatt LG, et al. Among authors: kuduk sd. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127589. doi: 10.1016/j.bmcl.2020.127589. Epub 2020 Sep 29. Bioorg Med Chem Lett. 2020. PMID: 33007394

6

Diazepinone HBV capsid assembly modulators.

Kuduk SD, DeRatt LG, Stoops B, Shaffer P, Lam AM, Espiritu C, Vogel R, Lau V, Flores OA, Hartman GD. Kuduk SD, et al. Bioorg Med Chem Lett. 2022 Sep 15;72:128823. doi: 10.1016/j.bmcl.2022.128823. Epub 2022 May 27. Bioorg Med Chem Lett. 2022. PMID: 35644301

7

N-Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia.

Cisar JS, Pietsch C, DeRatt LG, Jacoby E, Kazmi F, Keohane C, Legenski K, Matico R, Shaffer P, Simonnet Y, Tanner A, Wang CY, Wang W, Attar R, Edwards JP, Kuduk SD. Cisar JS, et al. Among authors: kuduk sd. J Med Chem. 2022 Aug 25;65(16):11241-11256. doi: 10.1021/acs.jmedchem.2c00788. Epub 2022 Aug 4. J Med Chem. 2022. PMID: 35925768

8

SAR studies in the sulfonyl carboxamide class of HBV capsid assembly modulators.

Kuduk SD, Lam AM, Espiritu C, Vogel R, Lau V, Klumpp K, Flores OA, Hartman GD. Kuduk SD, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2405-2409. doi: 10.1016/j.bmcl.2019.05.029. Epub 2019 May 16. Bioorg Med Chem Lett. 2019. PMID: 31227344

9

P450s under Restriction (PURE) Screen Using HepaRG and Primary Human Hepatocytes for Discovery of Novel HBV Antivirals.

Hartman GD, Kuduk SD, Espiritu C, Lam AM. Hartman GD, et al. Among authors: kuduk sd. ACS Med Chem Lett. 2020 Feb 26;11(10):1919-1927. doi: 10.1021/acsmedchemlett.9b00630. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062174 Free PMC article.

10

Identification of a new class of HBV capsid assembly modulator.

Kuduk SD, Stoops B, Alexander R, Lam AM, Espiritu C, Vogel R, Lau V, Klumpp K, Flores OA, Hartman GD. Kuduk SD, et al. Bioorg Med Chem Lett. 2021 May 1;39:127848. doi: 10.1016/j.bmcl.2021.127848. Epub 2021 Feb 18. Bioorg Med Chem Lett. 2021. PMID: 33610748

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