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Novel 5-Nitrofuran-Tagged Imidazo-Fused Azines and Azoles Amenable by the Groebke-Blackburn-Bienaymé Multicomponent Reaction: Activity Profile against ESKAPE Pathogens and Mycobacteria.
Sapegin A, Rogacheva E, Kraeva L, Gureev M, Dogonadze M, Vinogradova T, Yablonsky P, Balalaie S, Baykov SV, Krasavin M. Sapegin A, et al. Among authors: krasavin m. Biomedicines. 2022 Sep 6;10(9):2203. doi: 10.3390/biomedicines10092203. Biomedicines. 2022. PMID: 36140307 Free PMC article.
Conjugation of a 5-nitrofuran-2-oyl moiety to aminoalkylimidazoles produces non-toxic nitrofurans that are efficacious in vitro and in vivo against multidrug-resistant Mycobacterium tuberculosis.
Krasavin M, Lukin A, Vedekhina T, Manicheva O, Dogonadze M, Vinogradova T, Zabolotnykh N, Rogacheva E, Kraeva L, Yablonsky P. Krasavin M, et al. Eur J Med Chem. 2018 Sep 5;157:1115-1126. doi: 10.1016/j.ejmech.2018.08.068. Epub 2018 Aug 29. Eur J Med Chem. 2018. PMID: 30179748
154 results