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Gliotoxin from Aspergillus fumigatus Abrogates Leukotriene B4 Formation through Inhibition of Leukotriene A4 Hydrolase.
König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O. König S, et al. Among authors: kramer j. Cell Chem Biol. 2019 Apr 18;26(4):524-534.e5. doi: 10.1016/j.chembiol.2019.01.001. Epub 2019 Feb 7. Cell Chem Biol. 2019. PMID: 30745237 Free article.
Phosphatase activity of soluble epoxide hydrolase.
Kramer J, Proschak E. Kramer J, et al. Prostaglandins Other Lipid Mediat. 2017 Nov;133:88-92. doi: 10.1016/j.prostaglandins.2017.07.002. Epub 2017 Jul 17. Prostaglandins Other Lipid Mediat. 2017. PMID: 28729091 Review.
Thermodynamic properties of leukotriene A4 hydrolase inhibitors.
Wittmann SK, Kalinowsky L, Kramer JS, Bloecher R, Knapp S, Steinhilber D, Pogoryelov D, Proschak E, Heering J. Wittmann SK, et al. Among authors: kramer js. Bioorg Med Chem. 2016 Nov 1;24(21):5243-5248. doi: 10.1016/j.bmc.2016.08.047. Epub 2016 Aug 26. Bioorg Med Chem. 2016. PMID: 27651294
Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA4 Hydrolase.
Hiesinger K, Schott A, Kramer JS, Blöcher R, Witt F, Wittmann SK, Steinhilber D, Pogoryelov D, Gerstmeier J, Werz O, Proschak E. Hiesinger K, et al. Among authors: kramer js. ACS Med Chem Lett. 2019 Oct 30;11(3):298-302. doi: 10.1021/acsmedchemlett.9b00330. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184960 Free PMC article.
Compilation and evaluation of a fatty acid mimetics screening library.
Ehrler JHM, Brunst S, Tjaden A, Kilu W, Heering J, Hernandez-Olmos V, Krommes A, Kramer JS, Steinhilber D, Schubert-Zsilavecz M, Müller S, Merk D, Proschak E. Ehrler JHM, et al. Among authors: kramer js. Biochem Pharmacol. 2022 Oct;204:115191. doi: 10.1016/j.bcp.2022.115191. Epub 2022 Jul 27. Biochem Pharmacol. 2022. PMID: 35907497
Development and in vitro Profiling of Dual FXR/LTA4H Modulators.
Schierle S, Brunst S, Helmstädter M, Ebert R, Kramer JS, Steinhilber D, Proschak E, Merk D. Schierle S, et al. ChemMedChem. 2021 Aug 5;16(15):2366-2374. doi: 10.1002/cmdc.202100118. Epub 2021 May 24. ChemMedChem. 2021. PMID: 33856122 Free PMC article.
3,397 results