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Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
Hamon Y, Legowska M, Hervé V, Dallet-Choisy S, Marchand-Adam S, Vanderlynden L, Demonte M, Williams R, Scott CJ, Si-Tahar M, Heuzé-Vourc'h N, Lalmanach G, Jenne DE, Lesner A, Gauthier F, Korkmaz B. Hamon Y, et al. Among authors: korkmaz b. J Biol Chem. 2016 Apr 15;291(16):8486-99. doi: 10.1074/jbc.M115.707109. Epub 2016 Feb 16. J Biol Chem. 2016. PMID: 26884336 Free PMC article.
Neutrophils can disarm NK cell response through cleavage of NKp46.
Valayer A, Brea D, Lajoie L, Avezard L, Combes-Soia L, Labas V, Korkmaz B, Thibault G, Baranek T, Si-Tahar M. Valayer A, et al. Among authors: korkmaz b. J Leukoc Biol. 2017 Jan;101(1):253-259. doi: 10.1189/jlb.3AB0316-140RR. Epub 2016 Sep 1. J Leukoc Biol. 2017. PMID: 27587403
Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.
Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc'h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B. Guarino C, et al. Among authors: korkmaz b. Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009. Epub 2017 Feb 11. Biochem Pharmacol. 2017. PMID: 28193451
4C3 Human Monoclonal Antibody: A Proof of Concept for Non-pathogenic Proteinase 3 Anti-neutrophil Cytoplasmic Antibodies in Granulomatosis With Polyangiitis.
Granel J, Lemoine R, Morello E, Gallais Y, Mariot J, Drapeau M, Musnier A, Poupon A, Pugnière M, Seren S, Nouar D, Gouilleux-Gruart V, Watier H, Korkmaz B, Hoarau C. Granel J, et al. Among authors: korkmaz b. Front Immunol. 2020 Sep 25;11:573040. doi: 10.3389/fimmu.2020.573040. eCollection 2020. Front Immunol. 2020. PMID: 33101296 Free PMC article.
Proteinase 3 phosphonic inhibitors.
Grzywa R, Lesner A, Korkmaz B, Sieńczyk M. Grzywa R, et al. Among authors: korkmaz b. Biochimie. 2019 Nov;166:142-149. doi: 10.1016/j.biochi.2019.03.005. Epub 2019 Mar 13. Biochimie. 2019. PMID: 30876969 Review.
162 results