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ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Scoyni F, Sitnikova V, Giudice L, Korhonen P, Trevisan DM, Hernandez de Sande A, Gomez-Budia M, Giniatullina R, Ugidos IF, Dhungana H, Pistono C, Korvenlaita N, Välimäki NN, Kangas SM, Hiltunen AE, Gribchenko E, Kaikkonen-Määttä MU, Koistinaho J, Ylä-Herttuala S, Hinttala R, Venø MT, Su J, Stoffel M, Schaefer A, Rajewsky N, Kjems J, LaPierre MP, Piwecka M, Jolkkonen J, Giniatullin R, Hansen TB, Malm T. Scoyni F, et al. Among authors: korhonen p. Cell Rep. 2024 Mar 26;43(3):113862. doi: 10.1016/j.celrep.2024.113862. Epub 2024 Mar 5. Cell Rep. 2024. PMID: 38446664 Free article.
Peripheral inflammation preceeding ischemia impairs neuronal survival through mechanisms involving miR-127 in aged animals.
Loppi S, Korhonen P, Bouvy-Liivrand M, Caligola S, Turunen TA, Turunen MP, Hernandez de Sande A, Kołosowska N, Scoyni F, Rosell A, García-Berrocoso T, Lemarchant S, Dhungana H, Montaner J, Koistinaho J, Kanninen KM, Kaikkonen MU, Giugno R, Heinäniemi M, Malm T. Loppi S, et al. Among authors: korhonen p. Aging Cell. 2021 Jan;20(1):e13287. doi: 10.1111/acel.13287. Epub 2020 Dec 28. Aging Cell. 2021. PMID: 33369048 Free PMC article.
Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation.
Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, Ylä-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T. Kolosowska N, et al. Among authors: korhonen p. J Neuroinflammation. 2020 Jun 19;17(1):194. doi: 10.1186/s12974-020-01870-w. J Neuroinflammation. 2020. PMID: 32560730 Free PMC article.
Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia.
Korvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T. Korvenlaita N, et al. Among authors: korhonen p. J Extracell Vesicles. 2023 Jan;12(1):e12297. doi: 10.1002/jev2.12297. J Extracell Vesicles. 2023. PMID: 36594832 Free PMC article.
Alzheimer's disease-induced phagocytic microglia express a specific profile of coding and non-coding RNAs.
Scoyni F, Giudice L, Väänänen MA, Downes N, Korhonen P, Choo XY, Välimäki NN, Mäkinen P, Korvenlaita N, Rozemuller AJ, de Vries HE, Polo J, Turunen TA, Ylä-Herttuala S, Hansen TB, Grubman A, Kaikkonen MU, Malm T. Scoyni F, et al. Among authors: korhonen p. Alzheimers Dement. 2024 Feb;20(2):954-974. doi: 10.1002/alz.13502. Epub 2023 Oct 12. Alzheimers Dement. 2024. PMID: 37828821 Free PMC article.
Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.
Ohtonen S, Giudice L, Jäntti H, Fazaludeen MF, Shakirzyanova A, Gómez-Budia M, Välimäki NN, Niskanen J, Korvenlaita N, Fagerlund I, Koistinaho J, Amiry-Moghaddam M, Savchenko E, Roybon L, Lehtonen Š, Korhonen P, Malm T. Ohtonen S, et al. Among authors: korhonen p. Sci Rep. 2023 Dec 13;13(1):22118. doi: 10.1038/s41598-023-49294-9. Sci Rep. 2023. PMID: 38092815 Free PMC article.
Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy.
Huuskonen MT, Loppi S, Dhungana H, Keksa-Goldsteine V, Lemarchant S, Korhonen P, Wojciechowski S, Pollari E, Valonen P, Koponen J, Takashima A, Landreth G, Goldsteins G, Malm T, Koistinaho J, Kanninen KM. Huuskonen MT, et al. Among authors: korhonen p. Sci Rep. 2016 Sep 14;6:33176. doi: 10.1038/srep33176. Sci Rep. 2016. PMID: 27624652 Free PMC article.
430 results