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Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model.
Aging (Albany NY). 2019 Dec 4;11(23):11591-11608. doi: 10.18632/aging.102558. Epub 2019 Dec 4.
Aging (Albany NY). 2019.
PMID: 31804189
Free PMC article.
Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines.
Kondengaden SM, Luo LF, Huang K, Zhu M, Zang L, Bataba E, Wang R, Luo C, Wang B, Li KK, Wang PG.
Kondengaden SM, et al.
Eur J Med Chem. 2016 Oct 21;122:382-393. doi: 10.1016/j.ejmech.2016.06.028. Epub 2016 Jun 21.
Eur J Med Chem. 2016.
PMID: 27393948
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Structure based design, synthesis and activity studies of small hybrid molecules as HDAC and G9a dual inhibitors.
Zang L, Kondengaden SM, Zhang Q, Li X, Sigalapalli DK, Kondengadan SM, Huang K, Li KK, Li S, Xiao Z, Wen L, Zhu H, Babu BN, Wang L, Che F, Wang PG.
Zang L, et al. Among authors: kondengaden sm.
Oncotarget. 2017 Jun 28;8(38):63187-63207. doi: 10.18632/oncotarget.18730. eCollection 2017 Sep 8.
Oncotarget. 2017.
PMID: 28968981
Free PMC article.
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Two-step enzymatic synthesis of 6-deoxy-L-psicose.
Wen L, Huang K, Zheng Y, Fang J, Kondengaden SM, Wang PG.
Wen L, et al. Among authors: kondengaden sm.
Tetrahedron Lett. 2016 Aug 24;57(34):3819-3822. doi: 10.1016/j.tetlet.2016.07.015. Epub 2016 Jul 6.
Tetrahedron Lett. 2016.
PMID: 27546917
Free PMC article.
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Potential Epigenetic-Based Therapeutic Targets for Glioma.
Zang L, Kondengaden SM, Che F, Wang L, Heng X.
Zang L, et al. Among authors: kondengaden sm.
Front Mol Neurosci. 2018 Nov 15;11:408. doi: 10.3389/fnmol.2018.00408. eCollection 2018.
Front Mol Neurosci. 2018.
PMID: 30498431
Free PMC article.
Review.
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Chemoenzymatic Synthesis of a Library of Human Milk Oligosaccharides.
Xiao Z, Guo Y, Liu Y, Li L, Zhang Q, Wen L, Wang X, Kondengaden SM, Wu Z, Zhou J, Cao X, Li X, Ma C, Wang PG.
Xiao Z, et al. Among authors: kondengaden sm.
J Org Chem. 2016 Jul 15;81(14):5851-65. doi: 10.1021/acs.joc.6b00478. Epub 2016 Jun 29.
J Org Chem. 2016.
PMID: 27305319
Free PMC article.
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Two-Step Chemoenzymatic Detection of N-Acetylneuraminic Acid-α(2-3)-Galactose Glycans.
Wen L, Zheng Y, Jiang K, Zhang M, Kondengaden SM, Li S, Huang K, Li J, Song J, Wang PG.
Wen L, et al. Among authors: kondengaden sm.
J Am Chem Soc. 2016 Sep 14;138(36):11473-6. doi: 10.1021/jacs.6b07132. Epub 2016 Aug 30.
J Am Chem Soc. 2016.
PMID: 27554522
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Machine-Driven Chemoenzymatic Synthesis of Glycopeptide.
Zhang J, Liu D, Saikam V, Gadi MR, Gibbons C, Fu X, Song H, Yu J, Kondengaden SM, Wang PG, Wen L.
Zhang J, et al. Among authors: kondengaden sm.
Angew Chem Int Ed Engl. 2020 Nov 2;59(45):19825-19829. doi: 10.1002/anie.202001124. Epub 2020 Aug 31.
Angew Chem Int Ed Engl. 2020.
PMID: 32677091
Free PMC article.
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