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Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancer.
Martincuks A, Zhang C, Austria T, Li YJ, Huang R, Lugo Santiago N, Kohut A, Zhao Q, Borrero RM, Shen B, Cristea M, Wang EW, Song M, Rodriguez-Rodriguez L, Yu H. Martincuks A, et al. Among authors: kohut a. J Immunother Cancer. 2024 Apr 5;12(4):e007716. doi: 10.1136/jitc-2023-007716. J Immunother Cancer. 2024. PMID: 38580335 Free PMC article.
Niraparib-induced STAT3 inhibition increases its antitumor effects.
Zhao Q, Kohut A, Li YJ, Martincuks A, Austria T, Zhang C, Santiago NL, Borrero RM, Phan XT, Melstrom L, Rodriguez-Rodriguez L, Yu H. Zhao Q, et al. Among authors: kohut a. Front Oncol. 2022 Oct 17;12:966492. doi: 10.3389/fonc.2022.966492. eCollection 2022. Front Oncol. 2022. PMID: 36324587 Free PMC article.
CLIC4 localizes to mitochondrial-associated membranes and mediates cardioprotection.
Ponnalagu D, Hamilton S, Sanghvi S, Antelo D, Schwieterman N, Hansra I, Xu X, Gao E, Edwards JC, Bansal SS, Wold LE, Terentyev D, Janssen PML, Hund TJ, Khan M, Kohut AR, Koch WJ, Singh H. Ponnalagu D, et al. Among authors: kohut ar. Sci Adv. 2022 Oct 21;8(42):eabo1244. doi: 10.1126/sciadv.abo1244. Epub 2022 Oct 21. Sci Adv. 2022. PMID: 36269835 Free PMC article.
Phase I trial of daily subcutaneous SPL-108 injections in combination with paclitaxel in patients with platinum resistant CD44+ advanced ovarian epithelial cancer.
Girda E, Hou J, Nelson D, Finlayson M, de Meritens AB, Chekmareiva M, Leiser A, Song M, Stephenson R, Chan N, Tergas AI, Vattakalam R, Wright JD, Yu H, Martincuks A, Kohut A, Palmer J, Rodriguez-Rodriguez L. Girda E, et al. Among authors: kohut a. Int J Gynecol Cancer. 2022 Jun 24;32(8):1032-8. doi: 10.1136/ijgc-2021-003316. Online ahead of print. Int J Gynecol Cancer. 2022. PMID: 35750354 Free PMC article.
139 results