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Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain.
Muratspahić E, Tomašević N, Koehbach J, Duerrauer L, Hadžić S, Castro J, Schober G, Sideromenos S, Clark RJ, Brierley SM, Craik DJ, Gruber CW. Muratspahić E, et al. Among authors: koehbach j. J Med Chem. 2021 Jul 8;64(13):9042-9055. doi: 10.1021/acs.jmedchem.1c00158. Epub 2021 Jun 23. J Med Chem. 2021. PMID: 34162205 Free PMC article.
Do plant cyclotides have potential as immunosuppressant peptides?
Gründemann C, Koehbach J, Huber R, Gruber CW. Gründemann C, et al. Among authors: koehbach j. J Nat Prod. 2012 Feb 24;75(2):167-74. doi: 10.1021/np200722w. Epub 2012 Jan 24. J Nat Prod. 2012. PMID: 22272797 Free PMC article.
Immunosuppressive activity of an aqueous Viola tricolor herbal extract.
Hellinger R, Koehbach J, Fedchuk H, Sauer B, Huber R, Gruber CW, Gründemann C. Hellinger R, et al. Among authors: koehbach j. J Ethnopharmacol. 2014;151(1):299-306. doi: 10.1016/j.jep.2013.10.044. Epub 2013 Nov 8. J Ethnopharmacol. 2014. PMID: 24216163 Free PMC article.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design.
Koehbach J, O'Brien M, Muttenthaler M, Miazzo M, Akcan M, Elliott AG, Daly NL, Harvey PJ, Arrowsmith S, Gunasekera S, Smith TJ, Wray S, Göransson U, Dawson PE, Craik DJ, Freissmuth M, Gruber CW. Koehbach J, et al. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21183-8. doi: 10.1073/pnas.1311183110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248349 Free PMC article.
From ethnopharmacology to drug design.
Koehbach J, Gruber CW. Koehbach J, et al. Commun Integr Biol. 2013 Nov 1;6(6):e27583. doi: 10.4161/cib.27583. Epub 2014 Jan 8. Commun Integr Biol. 2013. PMID: 24567782 Free PMC article.
34 results