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RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation.
Kuvardina ON, Herglotz J, Kolodziej S, Kohrs N, Herkt S, Wojcik B, Oellerich T, Corso J, Behrens K, Kumar A, Hussong H, Urlaub H, Koch J, Serve H, Bonig H, Stocking C, Rieger MA, Lausen J. Kuvardina ON, et al. Among authors: koch j. Blood. 2015 Jun 4;125(23):3570-9. doi: 10.1182/blood-2014-11-610519. Epub 2015 Apr 24. Blood. 2015. PMID: 25911237 Free PMC article.
Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity.
Wichmann C, Becker Y, Chen-Wichmann L, Vogel V, Vojtkova A, Herglotz J, Moore S, Koch J, Lausen J, Mäntele W, Gohlke H, Grez M. Wichmann C, et al. Among authors: koch j. Blood. 2010 Jul 29;116(4):603-13. doi: 10.1182/blood-2009-10-248047. Epub 2010 Apr 29. Blood. 2010. PMID: 20430957 Free article.
Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.
Schanda J, Lee CW, Wohlan K, Müller-Kuller U, Kunkel H, Coco IQ, Stein S, Metz A, Koch J, Lausen J, Platzbecker U, Medyouf H, Gohlke H, Heuser M, Eder M, Grez M, Scherr M, Wichmann C. Schanda J, et al. Among authors: koch j. Haematologica. 2017 May;102(5):e170-e174. doi: 10.3324/haematol.2016.161570. Epub 2017 Feb 2. Haematologica. 2017. PMID: 28154087 Free PMC article. No abstract available.
A soluble fragment of the tumor antigen BCL2-associated athanogene 6 (BAG-6) is essential and sufficient for inhibition of NKp30 receptor-dependent cytotoxicity of natural killer cells.
Binici J, Hartmann J, Herrmann J, Schreiber C, Beyer S, Güler G, Vogel V, Tumulka F, Abele R, Mäntele W, Koch J. Binici J, et al. Among authors: koch j. J Biol Chem. 2013 Nov 29;288(48):34295-303. doi: 10.1074/jbc.M113.483602. Epub 2013 Oct 16. J Biol Chem. 2013. PMID: 24133212 Free PMC article.
The stalk domain and the glycosylation status of the activating natural killer cell receptor NKp30 are important for ligand binding.
Hartmann J, Tran TV, Kaudeer J, Oberle K, Herrmann J, Quagliano I, Abel T, Cohnen A, Gatterdam V, Jacobs A, Wollscheid B, Tampé R, Watzl C, Diefenbach A, Koch J. Hartmann J, et al. Among authors: koch j. J Biol Chem. 2012 Sep 7;287(37):31527-39. doi: 10.1074/jbc.M111.304238. Epub 2012 Jul 17. J Biol Chem. 2012. PMID: 22807449 Free PMC article.
BAG-6, a jack of all trades in health and disease.
Binici J, Koch J. Binici J, et al. Among authors: koch j. Cell Mol Life Sci. 2014 May;71(10):1829-37. doi: 10.1007/s00018-013-1522-y. Epub 2013 Dec 4. Cell Mol Life Sci. 2014. PMID: 24305946 Review.
1,788 results