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Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity.
Wichmann C, Becker Y, Chen-Wichmann L, Vogel V, Vojtkova A, Herglotz J, Moore S, Koch J, Lausen J, Mäntele W, Gohlke H, Grez M. Wichmann C, et al. Among authors: koch j. Blood. 2010 Jul 29;116(4):603-13. doi: 10.1182/blood-2009-10-248047. Epub 2010 Apr 29. Blood. 2010. PMID: 20430957 Free article.
RUNX1 represses the erythroid gene expression program during megakaryocytic differentiation.
Kuvardina ON, Herglotz J, Kolodziej S, Kohrs N, Herkt S, Wojcik B, Oellerich T, Corso J, Behrens K, Kumar A, Hussong H, Urlaub H, Koch J, Serve H, Bonig H, Stocking C, Rieger MA, Lausen J. Kuvardina ON, et al. Among authors: koch j. Blood. 2015 Jun 4;125(23):3570-9. doi: 10.1182/blood-2014-11-610519. Epub 2015 Apr 24. Blood. 2015. PMID: 25911237 Free PMC article.
Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.
Schanda J, Lee CW, Wohlan K, Müller-Kuller U, Kunkel H, Coco IQ, Stein S, Metz A, Koch J, Lausen J, Platzbecker U, Medyouf H, Gohlke H, Heuser M, Eder M, Grez M, Scherr M, Wichmann C. Schanda J, et al. Among authors: koch j. Haematologica. 2017 May;102(5):e170-e174. doi: 10.3324/haematol.2016.161570. Epub 2017 Feb 2. Haematologica. 2017. PMID: 28154087 Free PMC article. No abstract available.
A soluble fragment of the tumor antigen BCL2-associated athanogene 6 (BAG-6) is essential and sufficient for inhibition of NKp30 receptor-dependent cytotoxicity of natural killer cells.
Binici J, Hartmann J, Herrmann J, Schreiber C, Beyer S, Güler G, Vogel V, Tumulka F, Abele R, Mäntele W, Koch J. Binici J, et al. Among authors: koch j. J Biol Chem. 2013 Nov 29;288(48):34295-303. doi: 10.1074/jbc.M113.483602. Epub 2013 Oct 16. J Biol Chem. 2013. PMID: 24133212 Free PMC article.
Inhibition of HIV-1 by a peptide ligand of the genomic RNA packaging signal Psi.
Dietz J, Koch J, Kaur A, Raja C, Stein S, Grez M, Pustowka A, Mensch S, Ferner J, Möller L, Bannert N, Tampé R, Divita G, Mély Y, Schwalbe H, Dietrich U. Dietz J, et al. Among authors: koch j. ChemMedChem. 2008 May;3(5):749-55. doi: 10.1002/cmdc.200700194. ChemMedChem. 2008. PMID: 18205165
Peptides as drugs: from screening to application.
Dietrich U, Dürr R, Koch J. Dietrich U, et al. Among authors: koch j. Curr Pharm Biotechnol. 2013;14(5):501-12. doi: 10.2174/13892010113149990205. Curr Pharm Biotechnol. 2013. PMID: 22429133 Review.
1,788 results