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Surface patches induce nonspecific binding and phase separation of antibodies.
Ausserwöger H, Krainer G, Welsh TJ, Thorsteinson N, de Csilléry E, Sneideris T, Schneider MM, Egebjerg T, Invernizzi G, Herling TW, Lorenzen N, Knowles TPJ. Ausserwöger H, et al. Among authors: knowles tpj. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2210332120. doi: 10.1073/pnas.2210332120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011217 Free PMC article.
Crucial role of nonspecific interactions in amyloid nucleation.
Šarić A, Chebaro YC, Knowles TP, Frenkel D. Šarić A, et al. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17869-74. doi: 10.1073/pnas.1410159111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453085 Free PMC article.
Force generation by the growth of amyloid aggregates.
Herling TW, Garcia GA, Michaels TC, Grentz W, Dean J, Shimanovich U, Gang H, Müller T, Kav B, Terentjev EM, Dobson CM, Knowles TP. Herling TW, et al. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9524-9. doi: 10.1073/pnas.1417326112. Epub 2015 Jul 20. Proc Natl Acad Sci U S A. 2015. PMID: 26195762 Free PMC article.
386 results