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An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.
Seifert U, Marañón C, Shmueli A, Desoutter JF, Wesoloski L, Janek K, Henklein P, Diescher S, Andrieu M, de la Salle H, Weinschenk T, Schild H, Laderach D, Galy A, Haas G, Kloetzel PM, Reiss Y, Hosmalin A. Seifert U, et al. Among authors: kloetzel pm. Nat Immunol. 2003 Apr;4(4):375-9. doi: 10.1038/ni905. Epub 2003 Feb 24. Nat Immunol. 2003. PMID: 12598896
Hepatitis C virus mutation affects proteasomal epitope processing.
Seifert U, Liermann H, Racanelli V, Halenius A, Wiese M, Wedemeyer H, Ruppert T, Rispeter K, Henklein P, Sijts A, Hengel H, Kloetzel PM, Rehermann B. Seifert U, et al. Among authors: kloetzel pm. J Clin Invest. 2004 Jul;114(2):250-9. doi: 10.1172/JCI20985. J Clin Invest. 2004. PMID: 15254592 Free PMC article.
MAPPP: MHC class I antigenic peptide processing prediction.
Hakenberg J, Nussbaum AK, Schild H, Rammensee HG, Kuttler C, Holzhütter HG, Kloetzel PM, Kaufmann SH, Mollenkopf HJ. Hakenberg J, et al. Among authors: kloetzel pm. Appl Bioinformatics. 2003;2(3):155-8. Appl Bioinformatics. 2003. PMID: 15130801
Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.
Textor A, Schmidt K, Kloetzel PM, Weißbrich B, Perez C, Charo J, Anders K, Sidney J, Sette A, Schumacher TN, Keller C, Busch DH, Seifert U, Blankenstein T. Textor A, et al. Among authors: kloetzel pm. J Exp Med. 2016 Oct 17;213(11):2333-2348. doi: 10.1084/jem.20160636. Epub 2016 Oct 3. J Exp Med. 2016. PMID: 27697836 Free PMC article.
Immunoproteasomes are important for proteostasis in immune responses.
Ebstein F, Voigt A, Lange N, Warnatsch A, Schröter F, Prozorovski T, Kuckelkorn U, Aktas O, Seifert U, Kloetzel PM, Krüger E. Ebstein F, et al. Among authors: kloetzel pm. Cell. 2013 Feb 28;152(5):935-7. doi: 10.1016/j.cell.2013.02.018. Cell. 2013. PMID: 23452842 Free article. No abstract available.
216 results