Klein AN - Search Results

1

Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.

Shaykhalishahi H, Gauhar A, Wördehoff MM, Grüning CS, Klein AN, Bannach O, Stoldt M, Willbold D, Härd T, Hoyer W. Shaykhalishahi H, et al. Among authors: klein an. Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8837-40. doi: 10.1002/anie.201503018. Epub 2015 Jun 26. Angew Chem Int Ed Engl. 2015. PMID: 26119103

2

The off-rate of monomers dissociating from amyloid-β protofibrils.

Grüning CS, Klinker S, Wolff M, Schneider M, Toksöz K, Klein AN, Nagel-Steger L, Willbold D, Hoyer W. Grüning CS, et al. Among authors: klein an. J Biol Chem. 2013 Dec 27;288(52):37104-11. doi: 10.1074/jbc.M113.513432. Epub 2013 Nov 18. J Biol Chem. 2013. PMID: 24247242 Free PMC article.

3

Alternative conformations of the Tau repeat domain in complex with an engineered binding protein.

Grüning CSR, Mirecka EA, Klein AN, Mandelkow E, Willbold D, Marino SF, Stoldt M, Hoyer W. Grüning CSR, et al. Among authors: klein an. J Biol Chem. 2014 Aug 15;289(33):23209-23218. doi: 10.1074/jbc.M114.560920. Epub 2014 Jun 25. J Biol Chem. 2014. PMID: 24966331 Free PMC article.

4

Structural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous Trifluoroethanol.

Dammers C, Gremer L, Reiß K, Klein AN, Neudecker P, Hartmann R, Sun N, Demuth HU, Schwarten M, Willbold D. Dammers C, et al. Among authors: klein an. PLoS One. 2015 Nov 23;10(11):e0143647. doi: 10.1371/journal.pone.0143647. eCollection 2015. PLoS One. 2015. PMID: 26600248 Free PMC article.

5

The D-amino acid peptide D3 reduces amyloid fibril boosted HIV-1 infectivity.

Widera M, Klein AN, Cinar Y, Funke SA, Willbold D, Schaal H. Widera M, et al. Among authors: klein an. AIDS Res Ther. 2014 Jan 14;11(1):1. doi: 10.1186/1742-6405-11-1. AIDS Res Ther. 2014. PMID: 24422713 Free PMC article.

6

Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity.

Rudolph S, Klein AN, Tusche M, Schlosser C, Elfgen A, Brener O, Teunissen C, Gremer L, Funke SA, Kutzsche J, Willbold D. Rudolph S, et al. Among authors: klein an. PLoS One. 2016 Feb 3;11(2):e0147470. doi: 10.1371/journal.pone.0147470. eCollection 2016. PLoS One. 2016. PMID: 26840229 Free PMC article.

7

Optimization of d-Peptides for Aβ Monomer Binding Specificity Enhances Their Potential to Eliminate Toxic Aβ Oligomers.

Klein AN, Ziehm T, van Groen T, Kadish I, Elfgen A, Tusche M, Thomaier M, Reiss K, Brener O, Gremer L, Kutzsche J, Willbold D. Klein AN, et al. ACS Chem Neurosci. 2017 Sep 20;8(9):1889-1900. doi: 10.1021/acschemneuro.7b00045. Epub 2017 Jun 23. ACS Chem Neurosci. 2017. PMID: 28581708

8

Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination.

Klein AN, Ziehm T, Tusche M, Buitenhuis J, Bartnik D, Boeddrich A, Wiglenda T, Wanker E, Funke SA, Brener O, Gremer L, Kutzsche J, Willbold D. Klein AN, et al. PLoS One. 2016 Apr 22;11(4):e0153035. doi: 10.1371/journal.pone.0153035. eCollection 2016. PLoS One. 2016. PMID: 27105346 Free PMC article.

9

Structure characterization of unexpected covalent O-sulfonation and ion-pairing on an extremely hydrophilic peptide with CE-MS and FT-ICR-MS.

Pattky M, Nicolardi S, Santiago-Schübel B, Sydes D, van der Burgt YE, Klein AN, Jiang N, Mohrlüder J, Hänel K, Kutzsche J, Funke SA, Willbold D, Willbold S, Huhn C. Pattky M, et al. Among authors: klein an. Anal Bioanal Chem. 2015 Sep;407(22):6637-55. doi: 10.1007/s00216-015-8826-8. Epub 2015 Jun 28. Anal Bioanal Chem. 2015. PMID: 26123437

10

Correction: Competitive Mirror Image Phage Display Derived Peptide Modulates Amyloid Beta Aggregation and Toxicity.

Rudolph S, Klein AN, Tusche M, Schlosser C, Elfgen A, Brener O, Teunissen C, Gremer L, Funke SA, Kutzsche J, Willbold D. Rudolph S, et al. Among authors: klein an. PLoS One. 2016 Jul 12;11(7):e0159470. doi: 10.1371/journal.pone.0159470. eCollection 2016. PLoS One. 2016. PMID: 27403661 Free PMC article.

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