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The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil.
Kiweler N, Schwarz H, Nguyen A, Matschos S, Mullins C, Piée-Staffa A, Brachetti C, Roos WP, Schneider G, Linnebacher M, Brenner W, Krämer OH. Kiweler N, et al. Cell Biol Toxicol. 2023 Oct;39(5):2401-2419. doi: 10.1007/s10565-022-09731-3. Epub 2022 May 24. Cell Biol Toxicol. 2023. PMID: 35608750 Free PMC article.
Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.
Wagner T, Kiweler N, Wolff K, Knauer SK, Brandl A, Hemmerich P, Dannenberg JH, Heinzel T, Schneider G, Krämer OH. Wagner T, et al. Among authors: kiweler n. Oncotarget. 2015 Mar 30;6(9):7123-35. doi: 10.18632/oncotarget.3344. Oncotarget. 2015. PMID: 25704882 Free PMC article.
Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells.
Schäfer C, Göder A, Beyer M, Kiweler N, Mahendrarajah N, Rauch A, Nikolova T, Stojanovic N, Wieczorek M, Reich TR, Tomicic MT, Linnebacher M, Sonnemann J, Dietrich S, Sellmer A, Mahboobi S, Heinzel T, Schneider G, Krämer OH. Schäfer C, et al. Among authors: kiweler n. Cell Signal. 2017 Jan;29:218-225. doi: 10.1016/j.cellsig.2016.11.002. Epub 2016 Nov 9. Cell Signal. 2017. PMID: 27838375
Interstrand Crosslink Repair as a Target for HDAC Inhibition.
Nikolova T, Kiweler N, Krämer OH. Nikolova T, et al. Among authors: kiweler n. Trends Pharmacol Sci. 2017 Sep;38(9):822-836. doi: 10.1016/j.tips.2017.05.009. Epub 2017 Jul 4. Trends Pharmacol Sci. 2017. PMID: 28687272 Review.
Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.
Pons M, Reichardt CM, Hennig D, Nathan A, Kiweler N, Stocking C, Wichmann C, Christmann M, Butter F, Reichardt S, Schneider G, Heinzel T, Englert C, Hartkamp J, Krämer OH, Mahendrarajah N. Pons M, et al. Among authors: kiweler n. Arch Toxicol. 2018 Jun;92(6):2119-2135. doi: 10.1007/s00204-018-2202-3. Epub 2018 Mar 27. Arch Toxicol. 2018. PMID: 29589053
15 results