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N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.
Lee J, Lee J, Kang M, Shin M, Kim JM, Kang SU, Lim JO, Choi HK, Suh YG, Park HG, Oh U, Kim HD, Park YH, Ha HJ, Kim YH, Toth A, Wang Y, Tran R, Pearce LV, Lundberg DJ, Blumberg PM. Lee J, et al. Among authors: kim yh, kim jm, kim hd. J Med Chem. 2003 Jul 3;46(14):3116-26. doi: 10.1021/jm030089u. J Med Chem. 2003. PMID: 12825950
Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity.
Lee J, Kang SU, Choi HK, Lee J, Lim JO, Kil MJ, Jin MK, Kim KP, Sung JH, Chung SJ, Ha HJ, Kim YH, Pearce LV, Tran R, Lundberg DJ, Wang Y, Toth A, Blumberg PM. Lee J, et al. Among authors: kim yh, kim kp. Bioorg Med Chem Lett. 2004 May 3;14(9):2291-7. doi: 10.1016/j.bmcl.2004.02.002. Bioorg Med Chem Lett. 2004. PMID: 15081027
Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs.
Suh YG, Lee KO, Moon SH, Seo SY, Lee YS, Kim SH, Paek SM, Kim YH, Lee YS, Jeong JM, Lee SJ, Kim SG. Suh YG, et al. Among authors: kim yh, kim sg, kim sh. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3487-90. doi: 10.1016/j.bmcl.2004.04.054. Bioorg Med Chem Lett. 2004. PMID: 15177458
Analysis of structure-activity relationships for the 'B-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists.
Lee J, Jin MK, Kang SU, Kim SY, Lee J, Shin M, Hwang J, Cho S, Choi YS, Choi HK, Kim SE, Suh YG, Lee YS, Kim YH, Ha HJ, Toth A, Pearce LV, Tran R, Szabo T, Welter JD, Lundberg DJ, Wang Y, Lazar J, Pavlyukovets VA, Morgan MA, Blumberg PM. Lee J, et al. Among authors: kim yh, kim se, kim sy. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4143-50. doi: 10.1016/j.bmcl.2005.06.006. Bioorg Med Chem Lett. 2005. PMID: 15993063
Analysis of structure-activity relationships for the 'A-region' of N-(4-t-butylbenzyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues as TRPV1 antagonists.
Lee J, Kang SU, Kil MJ, Shin M, Lim JO, Choi HK, Jin MK, Kim SY, Kim SE, Lee YS, Min KH, Kim YH, Ha HJ, Tran R, Welter JD, Wang Y, Szabo T, Pearce LV, Lundberg DJ, Toth A, Pavlyukovets VA, Morgan MA, Blumberg PM. Lee J, et al. Among authors: kim yh, kim se, kim sy. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4136-42. doi: 10.1016/j.bmcl.2005.06.009. Bioorg Med Chem Lett. 2005. PMID: 16005215
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