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Page 1
Extracellular fluid viscosity enhances cell migration and cancer dissemination.
Bera K, Kiepas A, Godet I, Li Y, Mehta P, Ifemembi B, Paul CD, Sen A, Serra SA, Stoletov K, Tao J, Shatkin G, Lee SJ, Zhang Y, Boen A, Mistriotis P, Gilkes DM, Lewis JD, Fan CM, Feinberg AP, Valverde MA, Sun SX, Konstantopoulos K. Bera K, et al. Among authors: kiepas a. Nature. 2022 Nov;611(7935):365-373. doi: 10.1038/s41586-022-05394-6. Epub 2022 Nov 2. Nature. 2022. PMID: 36323783 Free PMC article.
Sculpting Rupture-Free Nuclear Shapes in Fibrous Environments.
Jana A, Tran A, Gill A, Kiepas A, Kapania RK, Konstantopoulos K, Nain AS. Jana A, et al. Among authors: kiepas a. Adv Sci (Weinh). 2022 Sep;9(25):e2203011. doi: 10.1002/advs.202203011. Epub 2022 Jul 21. Adv Sci (Weinh). 2022. PMID: 35863910 Free PMC article.
Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis.
Zhang Y, Li Y, Thompson KN, Stoletov K, Yuan Q, Bera K, Lee SJ, Zhao R, Kiepas A, Wang Y, Mistriotis P, Serra SA, Lewis JD, Valverde MA, Martin SS, Sun SX, Konstantopoulos K. Zhang Y, et al. Among authors: kiepas a. Nat Commun. 2022 Oct 17;13(1):6128. doi: 10.1038/s41467-022-33683-1. Nat Commun. 2022. PMID: 36253369 Free PMC article.
Invasive growth of brain metastases is linked to CHI3L1 release from pSTAT3-positive astrocytes.
Dankner M, Maritan SM, Priego N, Kruck G, Nkili-Meyong A, Nadaf J, Zhuang R, Annis MG, Zuo D, Nowakowski A, Biondini M, Kiepas A, Mourcos C, Le P, Charron F, Inglebert Y, Savage P, Théret L, Guiot MC, McKinney RA, Muller WJ, Park M, Valiente M, Petrecca K, Siegel PM. Dankner M, et al. Among authors: kiepas a. Neuro Oncol. 2024 Jan 25:noae013. doi: 10.1093/neuonc/noae013. Online ahead of print. Neuro Oncol. 2024. PMID: 38271182
Cytoplasmic accumulation and plasma membrane association of anillin and Ect2 promote confined migration and invasion.
Tran AT, Wisniewski EO, Mistriotis P, Stoletov K, Parlani M, Amitrano A, Ifemembi B, Lee SJ, Bera K, Zhang Y, Tuntithavornwat S, Afthinos A, Kiepas A, Jamieson JJ, Zuo Y, Habib D, Wu PH, Martin SS, Gerecht S, Gu L, Lewis JD, Kalab P, Friedl P, Konstantopoulos K. Tran AT, et al. Among authors: kiepas a. Res Sq [Preprint]. 2024 Jan 10:rs.3.rs-3640969. doi: 10.21203/rs.3.rs-3640969/v1. Res Sq. 2024. PMID: 38260442 Free PMC article. Preprint.
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin.
Biondini M, Kiepas A, El-Houjeiri L, Annis MG, Hsu BE, Fortier AM, Morin G, Martina JA, Sirois I, Aguilar-Mahecha A, Gruosso T, McGuirk S, Rose AAN, Tokat UM, Johnson RM, Sahin O, Bareke E, St-Pierre J, Park M, Basik M, Majewski J, Puertollano R, Pause A, Huang S, Keler T, Siegel PM. Biondini M, et al. Among authors: kiepas a. Oncogene. 2022 Mar;41(12):1701-1717. doi: 10.1038/s41388-022-02206-z. Epub 2022 Feb 2. Oncogene. 2022. PMID: 35110681
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