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Selective Inhibition of the Hsp90α Isoform.
Mishra SJ, Khandelwal A, Banerjee M, Balch M, Peng S, Davis RE, Merfeld T, Munthali V, Deng J, Matts RL, Blagg BSJ. Mishra SJ, et al. Among authors: khandelwal a. Angew Chem Int Ed Engl. 2021 May 3;60(19):10547-10551. doi: 10.1002/anie.202015422. Epub 2021 Mar 26. Angew Chem Int Ed Engl. 2021. PMID: 33621416 Free PMC article.
Structure-guided design of an Hsp90β N-terminal isoform-selective inhibitor.
Khandelwal A, Kent CN, Balch M, Peng S, Mishra SJ, Deng J, Day VW, Liu W, Subramanian C, Cohen M, Holzbeierlein JM, Matts R, Blagg BSJ. Khandelwal A, et al. Nat Commun. 2018 Jan 30;9(1):425. doi: 10.1038/s41467-017-02013-1. Nat Commun. 2018. PMID: 29382832 Free PMC article.
Development of radamide analogs as Grp94 inhibitors.
Muth A, Crowley V, Khandelwal A, Mishra S, Zhao J, Hall J, Blagg BS. Muth A, et al. Among authors: khandelwal a. Bioorg Med Chem. 2014 Aug 1;22(15):4083-98. doi: 10.1016/j.bmc.2014.05.075. Epub 2014 Jun 12. Bioorg Med Chem. 2014. PMID: 25027801 Free PMC article.
Resorcinol-Based Grp94-Selective Inhibitors.
Khandelwal A, Crowley VM, Blagg BSJ. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018. doi: 10.1021/acsmedchemlett.7b00193. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057043 Free PMC article.
485 results