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Identification and optimization of a novel series of selective PIP5K inhibitors.
Andrews DM, Cartic S, Cosulich S, Divecha N, Faulder P, Flemington V, Kern O, Kettle JG, MacDonald E, McKelvie J, Pike KG, Roberts B, Rowlinson R, Smith JM, Stockley M, Swarbrick ME, Treinies I, Waring MJ. Andrews DM, et al. Among authors: kern o. Bioorg Med Chem. 2022 Jan 15;54:116557. doi: 10.1016/j.bmc.2021.116557. Epub 2021 Dec 12. Bioorg Med Chem. 2022. PMID: 34922306
Atmospheric CO2 forcing on Mediterranean biomes during the past 500 kyrs.
Koutsodendris A, Dakos V, Fletcher WJ, Knipping M, Kotthoff U, Milner AM, Müller UC, Kaboth-Bahr S, Kern OA, Kolb L, Vakhrameeva P, Wulf S, Christanis K, Schmiedl G, Pross J. Koutsodendris A, et al. Among authors: kern oa. Nat Commun. 2023 Mar 25;14(1):1664. doi: 10.1038/s41467-023-37388-x. Nat Commun. 2023. PMID: 36966144 Free PMC article.
The structures of two salivary proteins from the West Nile vector Culex quinquefasciatus reveal a beta-trefoil fold with putative sugar binding properties.
Kern O, Valenzuela Leon PC, Gittis AG, Bonilla B, Cruz P, Chagas AC, Ganesan S, Ribeiro JMC, Garboczi DN, Martin-Martin I, Calvo E. Kern O, et al. Curr Res Struct Biol. 2021 Mar 16;3:95-105. doi: 10.1016/j.crstbi.2021.03.001. eCollection 2021. Curr Res Struct Biol. 2021. PMID: 34235489 Free PMC article.
20 results